Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005507 | molecular_function | copper ion binding |
A | 0008131 | molecular_function | primary amine oxidase activity |
A | 0009308 | biological_process | amine metabolic process |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0046872 | molecular_function | metal ion binding |
A | 0048038 | molecular_function | quinone binding |
A | 0052595 | molecular_function | aliphatic amine oxidase activity |
B | 0005507 | molecular_function | copper ion binding |
B | 0008131 | molecular_function | primary amine oxidase activity |
B | 0009308 | biological_process | amine metabolic process |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0046872 | molecular_function | metal ion binding |
B | 0048038 | molecular_function | quinone binding |
B | 0052595 | molecular_function | aliphatic amine oxidase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CU A 701 |
Chain | Residue |
A | HIS431 |
A | HIS433 |
A | HIS592 |
A | CL702 |
A | HOH1370 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE CL A 702 |
Chain | Residue |
A | MET602 |
A | CU701 |
A | HOH824 |
A | HOH1370 |
A | 2TY382 |
A | HIS431 |
A | HIS433 |
A | HIS592 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL A 703 |
Chain | Residue |
A | HIS345 |
A | SER374 |
A | TYR387 |
A | HOH1150 |
A | HOH1347 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE NA A 704 |
Chain | Residue |
A | ALA93 |
A | ALA94 |
A | ARG148 |
A | SER562 |
B | VAL79 |
B | THR80 |
site_id | AC5 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE NA A 705 |
Chain | Residue |
A | ARG49 |
A | ASP440 |
A | MET441 |
A | PHE446 |
A | ASP581 |
A | ILE582 |
A | HOH831 |
site_id | AC6 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL A 706 |
Chain | Residue |
A | GLU347 |
A | ARG370 |
A | LYS401 |
A | GOL710 |
A | HOH852 |
A | HOH998 |
A | HOH1020 |
A | HOH1334 |
site_id | AC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A 707 |
Chain | Residue |
A | HIS515 |
A | ASP605 |
A | LYS610 |
A | HOH1243 |
A | HOH1266 |
A | HOH1340 |
site_id | AC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL A 708 |
Chain | Residue |
A | ASP161 |
A | HIS170 |
A | VAL197 |
A | ALA199 |
B | HOH1265 |
site_id | AC9 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE GOL A 709 |
Chain | Residue |
A | ILE39 |
A | ALA40 |
A | TYR41 |
A | LEU42 |
A | VAL251 |
A | ILE328 |
A | SER329 |
A | ASP330 |
A | HOH912 |
A | HOH982 |
site_id | BC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 710 |
Chain | Residue |
A | TRP349 |
A | ARG370 |
A | TYR389 |
A | GLU397 |
A | GLU399 |
A | GOL706 |
A | HOH1334 |
site_id | BC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CU B 701 |
Chain | Residue |
B | HIS431 |
B | HIS433 |
B | HIS592 |
B | CL702 |
B | HOH1319 |
site_id | BC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE CL B 702 |
Chain | Residue |
B | 2TY382 |
B | HIS431 |
B | HIS433 |
B | HIS592 |
B | MET602 |
B | CU701 |
B | HOH1309 |
B | HOH1319 |
site_id | BC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL B 703 |
Chain | Residue |
B | HIS345 |
B | SER374 |
B | TYR387 |
B | HOH1204 |
site_id | BC5 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE CL B 704 |
site_id | BC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE NA B 705 |
Chain | Residue |
B | ASP440 |
B | MET441 |
B | ASP581 |
B | ILE582 |
B | HOH885 |
site_id | BC7 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL B 706 |
Chain | Residue |
B | GLU347 |
B | ASP348 |
B | TRP349 |
B | ARG370 |
B | LYS401 |
B | HOH859 |
B | HOH1076 |
B | HOH1076 |
Functional Information from PROSITE/UniProt
site_id | PS01164 |
Number of Residues | 14 |
Details | COPPER_AMINE_OXID_1 Copper amine oxidase topaquinone signature. MVIsfftTigNYDY |
Chain | Residue | Details |
A | MET371-TYR384 | |
site_id | PS01165 |
Number of Residues | 14 |
Details | COPPER_AMINE_OXID_2 Copper amine oxidase copper-binding site signature. TfGltHFprvEDwP |
Chain | Residue | Details |
A | THR587-PRO600 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP298 | |
B | ASP298 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Schiff-base intermediate with substrate; via topaquinone => ECO:0000250|UniProtKB:P12807 |
Chain | Residue | Details |
A | 2TY382 | |
B | 2TY382 | |
Chain | Residue | Details |
A | TYR296 | |
B | TYR296 | |
Chain | Residue | Details |
A | ILE379 | |
B | ILE379 | |
site_id | SWS_FT_FI5 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000269|PubMed:9405045, ECO:0007744|PDB:1AV4, ECO:0007744|PDB:1AVL, ECO:0007744|PDB:1IU7, ECO:0007744|PDB:1IVU, ECO:0007744|PDB:1IVV, ECO:0007744|PDB:1IVW, ECO:0007744|PDB:1IVX, ECO:0007744|PDB:1RJO, ECO:0007744|PDB:1SIH, ECO:0007744|PDB:1SII, ECO:0007744|PDB:1UI8, ECO:0007744|PDB:1W4N, ECO:0007744|PDB:1W5Z, ECO:0007744|PDB:1W6C, ECO:0007744|PDB:1W6G, ECO:0007744|PDB:2BT3, ECO:0007744|PDB:2CFD, ECO:0007744|PDB:2CFG, ECO:0007744|PDB:2CFK, ECO:0007744|PDB:2CFL, ECO:0007744|PDB:2CFW, ECO:0007744|PDB:2CG0, ECO:0007744|PDB:2CG1, ECO:0007744|PDB:2CWT, ECO:0007744|PDB:2CWU, ECO:0007744|PDB:2CWV, ECO:0007744|PDB:2D1W, ECO:0007744|PDB:2E2T, ECO:0007744|PDB:2E2U, ECO:0007744|PDB:2E2V, ECO:0007744|PDB:2YX9, ECO:0007744|PDB:2ZL8, ECO:0007744|PDB:3AMO, ECO:0007744|PDB:3KII, ECO:0007744|PDB:3KN4, ECO:0007744|PDB:3WA2, ECO:0007744|PDB:3WA3 |
Chain | Residue | Details |
A | HIS431 | |
A | HIS433 | |
A | HIS592 | |
B | HIS431 | |
B | HIS433 | |
B | HIS592 | |
Chain | Residue | Details |
A | 2TY382 | |
B | 2TY382 | |