English 日本語简体中文繁體中文 한국어

✖

Menu

RCSB PDB PDBe BMRB Adv. Search Search help

Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3X3Y

Copper amine oxidase from Arthrobacter globiformis anaerobically reduced by histamine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005507	molecular_function	copper ion binding
A	0008131	molecular_function	primary methylamine oxidase activity
A	0009308	biological_process	amine metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016641	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
A	0046872	molecular_function	metal ion binding
A	0048038	molecular_function	quinone binding
B	0005507	molecular_function	copper ion binding
B	0008131	molecular_function	primary methylamine oxidase activity
B	0009308	biological_process	amine metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016641	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
B	0046872	molecular_function	metal ion binding
B	0048038	molecular_function	quinone binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU A 701

Chain	Residue
A	TYQ382
A	HIS431
A	HIS433
A	HIS592

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 702

Chain	Residue
B	HOH918
A	THR521
A	LEU522
A	THR538
A	HOH835
B	ARG457

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL A 703

Chain	Residue
A	ARG532
A	ARG533
A	THR554
A	PHE557
A	HIS561
A	SER562
A	GLY563
A	GLY564
A	ALA565
A	HOH801

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 704

Chain	Residue
A	GLU347
A	ARG370
A	LYS401
A	GOL706
A	HOH879
A	HOH1122
A	HOH1199

site_id	AC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 705

Chain	Residue
A	ASN368
A	TYR391
A	ASP393
A	THR395
A	LYS610
A	HOH1006
A	HOH1053
A	HOH1186
A	HOH1427

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 706

Chain	Residue
A	ARG370
A	GLU397
A	GLU399
A	GOL704
A	HOH1432
A	HOH1433

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 707

Chain	Residue
A	PRO136
A	GLY380
A	HOH872
A	HOH1429
A	HOH1436
B	LEU358
B	TRP359
B	HOH822

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 708

Chain	Residue
A	ASN126
A	ASP161
A	HIS170
A	VAL197
A	PRO198
A	ALA199

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 709

Chain	Residue
A	ASP440
A	MET441
A	ASP581
A	ILE582
A	HOH808

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE K A 710

Chain	Residue
A	VAL79
A	THR80
A	ALA93
A	ALA94
A	SER562
A	HOH864
A	HOH970

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU B 701

Chain	Residue
B	TYQ382
B	HIS431
B	HIS433
B	HIS592

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 702

Chain	Residue
B	ASN368
B	TYR391
B	ASP393
B	LYS610
B	HOH990
B	HOH1046
B	HOH1080

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 703

Chain	Residue
A	ASP525
B	ARG457
B	GLN458
B	THR459

site_id	BC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL B 704

Chain	Residue
A	TRP349
B	GLU347
B	ARG370
B	LYS401
B	HOH840
B	HOH850
B	HOH1179
B	HOH1353

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 705

Chain	Residue
A	HIS517
B	HIS517
B	HOH833
B	HOH1347

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA B 706

Chain	Residue
B	HOH814
B	ASP440
B	MET441
B	ASP581
B	ILE582

site_id	BC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE K B 707

Chain	Residue
B	VAL79
B	THR80
B	ALA93
B	ALA94
B	SER562
B	HOH1321
B	HOH1341

Functional Information from PROSITE/UniProt

site_id	PS01164
Number of Residues	14
Details	COPPER_AMINE_OXID_1 Copper amine oxidase topaquinone signature. MVIsfftTigNYDY

Chain	Residue	Details
A	MET371-TYR384

site_id	PS01165
Number of Residues	14
Details	COPPER_AMINE_OXID_2 Copper amine oxidase copper-binding site signature. TfGltHFprvEDwP

Chain	Residue	Details
A	THR587-PRO600

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000250\|UniProtKB:P12807

Chain	Residue	Details
A	ASP298
B	ASP298

site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Schiff-base intermediate with substrate; via topaquinone => ECO:0000250\|UniProtKB:P12807

Chain	Residue	Details
A	TYQ382
B	TYQ382

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P12807

Chain	Residue	Details
A	TYR296
B	TYR296

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P46883

Chain	Residue	Details
A	ILE379
B	ILE379

site_id	SWS_FT_FI5
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269\|PubMed:9405045, ECO:0007744\|PDB:1AV4, ECO:0007744\|PDB:1AVL, ECO:0007744\|PDB:1IU7, ECO:0007744\|PDB:1IVU, ECO:0007744\|PDB:1IVV, ECO:0007744\|PDB:1IVW, ECO:0007744\|PDB:1IVX, ECO:0007744\|PDB:1RJO, ECO:0007744\|PDB:1SIH, ECO:0007744\|PDB:1SII, ECO:0007744\|PDB:1UI8, ECO:0007744\|PDB:1W4N, ECO:0007744\|PDB:1W5Z, ECO:0007744\|PDB:1W6C, ECO:0007744\|PDB:1W6G, ECO:0007744\|PDB:2BT3, ECO:0007744\|PDB:2CFD, ECO:0007744\|PDB:2CFG, ECO:0007744\|PDB:2CFK, ECO:0007744\|PDB:2CFL, ECO:0007744\|PDB:2CFW, ECO:0007744\|PDB:2CG0, ECO:0007744\|PDB:2CG1, ECO:0007744\|PDB:2CWT, ECO:0007744\|PDB:2CWU, ECO:0007744\|PDB:2CWV, ECO:0007744\|PDB:2D1W, ECO:0007744\|PDB:2E2T, ECO:0007744\|PDB:2E2U, ECO:0007744\|PDB:2E2V, ECO:0007744\|PDB:2YX9, ECO:0007744\|PDB:2ZL8, ECO:0007744\|PDB:3AMO, ECO:0007744\|PDB:3KII, ECO:0007744\|PDB:3KN4, ECO:0007744\|PDB:3WA2, ECO:0007744\|PDB:3WA3

Chain	Residue	Details
A	HIS431
A	HIS433
A	HIS592
B	HIS431
B	HIS433
B	HIS592

site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: 2',4',5'-topaquinone => ECO:0000269\|PubMed:9405045

Chain	Residue	Details
A	TYQ382
B	TYQ382

238268

PDB entries from 2025-07-02

PDB statistics

PDBj update info

Contact PDBj

numon