Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005507 | molecular_function | copper ion binding |
A | 0008131 | molecular_function | primary amine oxidase activity |
A | 0009308 | biological_process | amine metabolic process |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0046872 | molecular_function | metal ion binding |
A | 0048038 | molecular_function | quinone binding |
A | 0052595 | molecular_function | aliphatic amine oxidase activity |
B | 0005507 | molecular_function | copper ion binding |
B | 0008131 | molecular_function | primary amine oxidase activity |
B | 0009308 | biological_process | amine metabolic process |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0046872 | molecular_function | metal ion binding |
B | 0048038 | molecular_function | quinone binding |
B | 0052595 | molecular_function | aliphatic amine oxidase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CU A 701 |
Chain | Residue |
A | TYQ382 |
A | HIS431 |
A | HIS433 |
A | HIS592 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A 702 |
Chain | Residue |
B | HOH918 |
A | THR521 |
A | LEU522 |
A | THR538 |
A | HOH835 |
B | ARG457 |
site_id | AC3 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE GOL A 703 |
Chain | Residue |
A | ARG532 |
A | ARG533 |
A | THR554 |
A | PHE557 |
A | HIS561 |
A | SER562 |
A | GLY563 |
A | GLY564 |
A | ALA565 |
A | HOH801 |
site_id | AC4 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 704 |
Chain | Residue |
A | GLU347 |
A | ARG370 |
A | LYS401 |
A | GOL706 |
A | HOH879 |
A | HOH1122 |
A | HOH1199 |
site_id | AC5 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE GOL A 705 |
Chain | Residue |
A | ASN368 |
A | TYR391 |
A | ASP393 |
A | THR395 |
A | LYS610 |
A | HOH1006 |
A | HOH1053 |
A | HOH1186 |
A | HOH1427 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A 706 |
Chain | Residue |
A | ARG370 |
A | GLU397 |
A | GLU399 |
A | GOL704 |
A | HOH1432 |
A | HOH1433 |
site_id | AC7 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL A 707 |
Chain | Residue |
A | PRO136 |
A | GLY380 |
A | HOH872 |
A | HOH1429 |
A | HOH1436 |
B | LEU358 |
B | TRP359 |
B | HOH822 |
site_id | AC8 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A 708 |
Chain | Residue |
A | ASN126 |
A | ASP161 |
A | HIS170 |
A | VAL197 |
A | PRO198 |
A | ALA199 |
site_id | AC9 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE NA A 709 |
Chain | Residue |
A | ASP440 |
A | MET441 |
A | ASP581 |
A | ILE582 |
A | HOH808 |
site_id | BC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE K A 710 |
Chain | Residue |
A | VAL79 |
A | THR80 |
A | ALA93 |
A | ALA94 |
A | SER562 |
A | HOH864 |
A | HOH970 |
site_id | BC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CU B 701 |
Chain | Residue |
B | TYQ382 |
B | HIS431 |
B | HIS433 |
B | HIS592 |
site_id | BC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL B 702 |
Chain | Residue |
B | ASN368 |
B | TYR391 |
B | ASP393 |
B | LYS610 |
B | HOH990 |
B | HOH1046 |
B | HOH1080 |
site_id | BC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL B 703 |
Chain | Residue |
A | ASP525 |
B | ARG457 |
B | GLN458 |
B | THR459 |
site_id | BC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL B 704 |
Chain | Residue |
A | TRP349 |
B | GLU347 |
B | ARG370 |
B | LYS401 |
B | HOH840 |
B | HOH850 |
B | HOH1179 |
B | HOH1353 |
site_id | BC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL B 705 |
Chain | Residue |
A | HIS517 |
B | HIS517 |
B | HOH833 |
B | HOH1347 |
site_id | BC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE NA B 706 |
Chain | Residue |
B | HOH814 |
B | ASP440 |
B | MET441 |
B | ASP581 |
B | ILE582 |
site_id | BC8 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE K B 707 |
Chain | Residue |
B | VAL79 |
B | THR80 |
B | ALA93 |
B | ALA94 |
B | SER562 |
B | HOH1321 |
B | HOH1341 |
Functional Information from PROSITE/UniProt
site_id | PS01164 |
Number of Residues | 14 |
Details | COPPER_AMINE_OXID_1 Copper amine oxidase topaquinone signature. MVIsfftTigNYDY |
Chain | Residue | Details |
A | MET371-TYR384 | |
site_id | PS01165 |
Number of Residues | 14 |
Details | COPPER_AMINE_OXID_2 Copper amine oxidase copper-binding site signature. TfGltHFprvEDwP |
Chain | Residue | Details |
A | THR587-PRO600 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP298 | |
B | ASP298 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Schiff-base intermediate with substrate; via topaquinone => ECO:0000250|UniProtKB:P12807 |
Chain | Residue | Details |
A | TYQ382 | |
B | TYQ382 | |
Chain | Residue | Details |
A | TYR296 | |
B | TYR296 | |
Chain | Residue | Details |
A | ILE379 | |
B | ILE379 | |
site_id | SWS_FT_FI5 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000269|PubMed:9405045, ECO:0007744|PDB:1AV4, ECO:0007744|PDB:1AVL, ECO:0007744|PDB:1IU7, ECO:0007744|PDB:1IVU, ECO:0007744|PDB:1IVV, ECO:0007744|PDB:1IVW, ECO:0007744|PDB:1IVX, ECO:0007744|PDB:1RJO, ECO:0007744|PDB:1SIH, ECO:0007744|PDB:1SII, ECO:0007744|PDB:1UI8, ECO:0007744|PDB:1W4N, ECO:0007744|PDB:1W5Z, ECO:0007744|PDB:1W6C, ECO:0007744|PDB:1W6G, ECO:0007744|PDB:2BT3, ECO:0007744|PDB:2CFD, ECO:0007744|PDB:2CFG, ECO:0007744|PDB:2CFK, ECO:0007744|PDB:2CFL, ECO:0007744|PDB:2CFW, ECO:0007744|PDB:2CG0, ECO:0007744|PDB:2CG1, ECO:0007744|PDB:2CWT, ECO:0007744|PDB:2CWU, ECO:0007744|PDB:2CWV, ECO:0007744|PDB:2D1W, ECO:0007744|PDB:2E2T, ECO:0007744|PDB:2E2U, ECO:0007744|PDB:2E2V, ECO:0007744|PDB:2YX9, ECO:0007744|PDB:2ZL8, ECO:0007744|PDB:3AMO, ECO:0007744|PDB:3KII, ECO:0007744|PDB:3KN4, ECO:0007744|PDB:3WA2, ECO:0007744|PDB:3WA3 |
Chain | Residue | Details |
A | HIS431 | |
A | HIS433 | |
A | HIS592 | |
B | HIS431 | |
B | HIS433 | |
B | HIS592 | |
Chain | Residue | Details |
A | TYQ382 | |
B | TYQ382 | |