3WZM
ZEN lactonase mutant complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009636 | biological_process | response to toxic substance |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0009636 | biological_process | response to toxic substance |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0009636 | biological_process | response to toxic substance |
| C | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ZER A 300 |
| Chain | Residue |
| A | GLY32 |
| A | PRO192 |
| A | PHE221 |
| A | HIS242 |
| A | HOH601 |
| A | LEU33 |
| A | ALA102 |
| A | SER103 |
| A | PRO128 |
| A | MET154 |
| A | TRP183 |
| A | TYR187 |
| A | ILE191 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE ZER B 300 |
| Chain | Residue |
| B | GLY32 |
| B | LEU33 |
| B | ALA102 |
| B | SER103 |
| B | PRO128 |
| B | MET154 |
| B | TRP183 |
| B | TYR187 |
| B | ILE191 |
| B | PRO192 |
| B | HIS242 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ZER C 300 |
| Chain | Residue |
| C | ASP31 |
| C | GLY32 |
| C | ALA102 |
| C | SER103 |
| C | PRO128 |
| C | LEU135 |
| C | MET154 |
| C | TRP183 |
| C | TYR187 |
| C | PRO188 |
| C | ILE191 |
| C | PRO192 |
| C | PHE221 |
| C | HOH421 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:28695844, ECO:0000269|DOI:10.1039/c4ra12111b |
| Chain | Residue | Details |
| A | ALA102 | |
| B | ALA102 | |
| C | ALA102 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | ACT_SITE: ACT_SITE => ECO:0000269|DOI:10.1039/c4ra12111b |
| Chain | Residue | Details |
| A | GLU126 | |
| A | HIS242 | |
| B | GLU126 | |
| B | HIS242 | |
| C | GLU126 | |
| C | HIS242 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28695844, ECO:0000269|DOI:10.1039/c4ra12111b, ECO:0000269|DOI:10.1021/acscatal.6b01826, ECO:0007744|PDB:3WZM, ECO:0007744|PDB:5C7Y, ECO:0007744|PDB:5IE4, ECO:0007744|PDB:5IE5, ECO:0007744|PDB:5IE6, ECO:0007744|PDB:5IE7 |
| Chain | Residue | Details |
| A | GLY32 | |
| B | GLY32 | |
| C | GLY32 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|Ref.3, ECO:0000269|Ref.6, ECO:0007744|PDB:5C7Y, ECO:0007744|PDB:6JRD |
| Chain | Residue | Details |
| A | ALA102 | |
| B | ALA102 | |
| C | ALA102 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|DOI:10.1039/c4ra12111b, ECO:0000269|DOI:10.1021/acscatal.6b01826, ECO:0000269|Ref.6, ECO:0007744|PDB:3WZM, ECO:0007744|PDB:5IE4, ECO:0007744|PDB:5IE5, ECO:0007744|PDB:5IE6, ECO:0007744|PDB:5IE7, ECO:0007744|PDB:6JRD |
| Chain | Residue | Details |
| A | SER103 | |
| A | TRP183 | |
| B | SER103 | |
| B | TRP183 | |
| C | SER103 | |
| C | TRP183 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|Ref.3, ECO:0007744|PDB:5C7Y |
| Chain | Residue | Details |
| A | TYR187 | |
| B | TYR187 | |
| C | TYR187 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|Ref.6, ECO:0007744|PDB:6JRD |
| Chain | Residue | Details |
| A | SER220 | |
| B | SER220 | |
| C | SER220 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|DOI:10.1039/c4ra12111b, ECO:0000269|DOI:10.1021/acscatal.6b01826, ECO:0007744|PDB:3WZM, ECO:0007744|PDB:5IE5, ECO:0007744|PDB:5IE6 |
| Chain | Residue | Details |
| A | HIS242 | |
| B | HIS242 | |
| C | HIS242 |
