3WJ8

Crystal Structure of DL-2-haloacid dehalogenase mutant with 2-bromo-2-methylpropionate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016787	molecular_function	hydrolase activity
A	0033976	molecular_function	2-haloacid dehalogenase (configuration-inverting) activity
B	0016787	molecular_function	hydrolase activity
B	0033976	molecular_function	2-haloacid dehalogenase (configuration-inverting) activity
D	0016787	molecular_function	hydrolase activity
D	0033976	molecular_function	2-haloacid dehalogenase (configuration-inverting) activity
E	0016787	molecular_function	hydrolase activity
E	0033976	molecular_function	2-haloacid dehalogenase (configuration-inverting) activity
F	0016787	molecular_function	hydrolase activity
F	0033976	molecular_function	2-haloacid dehalogenase (configuration-inverting) activity
G	0016787	molecular_function	hydrolase activity
G	0033976	molecular_function	2-haloacid dehalogenase (configuration-inverting) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE B2P A 401

Chain	Residue
A	TRP37
A	ILE274
A	ALA39
A	PHE40
A	GLY41
A	ALA192
A	SER193
A	ASN194
A	TYR270
A	PHE273

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 402

Chain	Residue
A	ARG210
A	PRO215
A	HOH512
D	LEU74

---

site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE B2P B 401

Chain	Residue
B	TRP37
B	ALA39
B	PHE40
B	GLY41
B	ALA192
B	SER193
B	ASN194
B	PHE273
B	ILE274

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL B 402

Chain	Residue
B	ARG210
B	HOH575
G	LEU74
G	HIS236
G	HOH523

---

site_id	AC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE B2P D 401

Chain	Residue
D	TRP37
D	ALA39
D	PHE40
D	GLY41
D	ALA192
D	SER193
D	ASN194
D	TYR270
D	ILE274

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL D 402

Chain	Residue
D	ARG210
D	HOH510
D	HOH595
F	LEU74

---

site_id	AC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE B2P E 401

Chain	Residue
E	TRP37
E	ALA39
E	PHE40
E	GLY41
E	ALA192
E	SER193
E	ASN194
E	TYR270
E	PHE273
E	ILE274

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL E 402

Chain	Residue
B	LEU74
B	HOH503
E	ARG210
E	PRO215
E	HOH521
E	HOH580

---

site_id	AC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE B2P F 401

Chain	Residue
F	TRP37
F	ALA39
F	PHE40
F	GLY41
F	SER193
F	ASN194
F	TYR270
F	PHE273
F	ILE274

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL F 402

Chain	Residue
A	LEU74
F	ARG210
F	PRO215
F	HOH512
F	HOH575

---

site_id	BC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE B2P G 401

Chain	Residue
G	TRP37
G	ALA39
G	PHE40
G	GLY41
G	ALA192
G	SER193
G	ASN194
G	TYR270
G	PHE273
G	ILE274

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL G 402

Chain	Residue
E	LEU74
G	ARG210
G	PRO215
G	HOH506

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