3SZM
STRUCTURE OF HUMAN MICROCEPHALIN (MCPH1) TANDEM BRCT DOMAINS IN COMPLEX WITH A GAMMA-H2AX PHOSPHOPEPTIDE
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | MOD_RES: Phosphoserine; by ATM, ATR and PRKDC => ECO:0000269|PubMed:10477747, ECO:0000269|PubMed:10734083, ECO:0000269|PubMed:10959836, ECO:0000269|PubMed:11673449, ECO:0000269|PubMed:12419185, ECO:0000269|PubMed:12607005, ECO:0000269|PubMed:12660252, ECO:0000269|PubMed:12697768, ECO:0000269|PubMed:14627815, ECO:0000269|PubMed:15059890, ECO:0000269|PubMed:15489221, ECO:0000269|PubMed:15613478, ECO:0000269|PubMed:17709392, ECO:0000269|PubMed:22154951, ECO:0000269|PubMed:9488723, ECO:0007744|PubMed:17525332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692 |
| Chain | Residue | Details |
| I | SEP139 | |
| J | SEP139 | |
| K | SEP139 | |
| L | SEP139 | |
| M | SEP139 | |
| N | SEP139 | |
| O | SEP139 | |
| P | SEP139 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | MOD_RES: Phosphotyrosine; by WSTF => ECO:0000269|PubMed:19092802, ECO:0000269|PubMed:19234442 |
| Chain | Residue | Details |
| I | TYR142 | |
| J | TYR142 | |
| K | TYR142 | |
| L | TYR142 | |
| M | TYR142 | |
| N | TYR142 | |
| O | TYR142 | |
| P | TYR142 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| I | LYS134 | |
| N | LYS134 | |
| O | LYS134 | |
| P | LYS134 | |
| J | LYS134 | |
| K | LYS134 | |
| L | LYS134 | |
| M | LYS134 |
