Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005242 | molecular_function | inward rectifier potassium channel activity |
| A | 0006813 | biological_process | potassium ion transport |
| A | 0016020 | cellular_component | membrane |
| B | 0005242 | molecular_function | inward rectifier potassium channel activity |
| B | 0006813 | biological_process | potassium ion transport |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PIO A 400 |
| Chain | Residue |
| A | LYS90 |
| A | TRP91 |
| A | ARG92 |
| A | LYS194 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE K A 501 |
| Chain | Residue |
| A | K502 |
| B | GLY156 |
| B | GLY156 |
| B | TYR157 |
| B | TYR157 |
| A | GLY156 |
| A | GLY156 |
| A | TYR157 |
| A | TYR157 |
| A | K502 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE K A 502 |
| Chain | Residue |
| A | ILE155 |
| A | ILE155 |
| A | GLY156 |
| A | GLY156 |
| A | K501 |
| A | K501 |
| A | K503 |
| A | K503 |
| B | ILE155 |
| B | ILE155 |
| B | GLY156 |
| B | GLY156 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE K A 503 |
| Chain | Residue |
| A | THR154 |
| A | THR154 |
| A | ILE155 |
| A | ILE155 |
| A | K502 |
| A | K502 |
| A | K504 |
| A | K504 |
| B | THR154 |
| B | THR154 |
| B | ILE155 |
| B | ILE155 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 504 |
| Chain | Residue |
| A | THR154 |
| A | THR154 |
| A | K503 |
| A | K503 |
| B | THR154 |
| B | THR154 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 48 |
| Details | TRANSMEM: Helical; Name=M1 => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG92-ILE116 | |
| B | ARG92-ILE116 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 62 |
| Details | TOPO_DOM: Extracellular => ECO:0000250 |
| Chain | Residue | Details |
| A | ALA117-GLY140 | |
| A | ARG160-GLU168 | |
| B | ALA117-GLY140 | |
| B | ARG160-GLU168 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 22 |
| Details | INTRAMEM: Helical; Pore-forming; Name=H5 => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE141-GLU152 | |
| B | PHE141-GLU152 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | INTRAMEM: Pore-forming => ECO:0000250 |
| Chain | Residue | Details |
| A | THR153-TYR159 | |
| B | THR153-TYR159 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 42 |
| Details | TRANSMEM: Helical; Name=M2 => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY169-CYS190 | |
| B | GLY169-CYS190 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | SITE: Role in the control of polyamine-mediated channel gating and in the blocking by intracellular magnesium => ECO:0000250 |
| Chain | Residue | Details |
| A | ASN184 | |
| B | ASN184 | |
