3SP9
Structural basis for iloprost as a dual PPARalpha/delta agonist
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE IL2 A 901 |
| Chain | Residue |
| A | HOH37 |
| A | HIS413 |
| A | TYR437 |
| A | HOH125 |
| A | PHE246 |
| A | ARG248 |
| A | THR252 |
| A | THR253 |
| A | HIS287 |
| A | ILE290 |
| A | VAL305 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE IL2 B 901 |
| Chain | Residue |
| B | HOH53 |
| B | PHE246 |
| B | ARG248 |
| B | CYS249 |
| B | THR252 |
| B | THR253 |
| B | HIS287 |
| B | PHE291 |
| B | VAL305 |
| B | VAL312 |
| B | HIS413 |
| B | TYR437 |
| B | HOH503 |
