Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005886 | cellular_component | plasma membrane |
A | 0008800 | molecular_function | beta-lactamase activity |
A | 0016787 | molecular_function | hydrolase activity |
A | 0017001 | biological_process | antibiotic catabolic process |
A | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
A | 0046677 | biological_process | response to antibiotic |
B | 0005886 | cellular_component | plasma membrane |
B | 0008800 | molecular_function | beta-lactamase activity |
B | 0016787 | molecular_function | hydrolase activity |
B | 0017001 | biological_process | antibiotic catabolic process |
B | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
B | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE PCZ A 3 |
Chain | Residue |
A | BB02 |
A | THR235 |
A | GLY236 |
A | ALA237 |
A | ALA238 |
A | SER240 |
A | ARG244 |
A | HOH368 |
A | HOH382 |
A | HOH11 |
A | ALA69 |
A | SER70 |
A | ASN104 |
A | SER130 |
A | ASN132 |
A | PRO167 |
A | LYS234 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE BB0 A 2 |
Chain | Residue |
A | CEF3 |
A | VAL103 |
A | ASN104 |
A | CYS166 |
A | GLU171 |
site_id | AC3 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE PCZ B 301 |
Chain | Residue |
B | HOH7 |
B | HOH12 |
B | ALA69 |
B | SER70 |
B | ASN104 |
B | SER130 |
B | ASN132 |
B | PRO167 |
B | THR235 |
B | GLY236 |
B | ALA237 |
B | ALA238 |
B | SER240 |
B | ARG244 |
site_id | AC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE BB0 B 2 |
Chain | Residue |
B | ASN104 |
B | CYS166 |
B | PRO167 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. FALDTGTNRTVA |
Chain | Residue | Details |
A | PHE47-ALA59 | |
site_id | PS00146 |
Number of Residues | 16 |
Details | BETA_LACTAMASE_A Beta-lactamase class-A active site. FaFASTiKaltVGVLL |
Chain | Residue | Details |
A | PHE66-LEU81 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Acyl-ester intermediate |
Chain | Residue | Details |
A | SER70 | |
B | SER70 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Proton acceptor |
Chain | Residue | Details |
A | GLU168 | |
B | GLU168 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | BINDING: |
Chain | Residue | Details |
A | LYS234 | |
B | LYS234 | |