3S0I
Crystal Structure of D48V mutant of Human Glycolipid Transfer Protein complexed with 3-O-sulfo galactosylceramide containing nervonoyl acyl chain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006869 | biological_process | lipid transport |
| A | 0008289 | molecular_function | lipid binding |
| A | 0017089 | molecular_function | glycolipid transfer activity |
| A | 0035621 | biological_process | ER to Golgi ceramide transport |
| A | 0035627 | biological_process | ceramide transport |
| A | 0035902 | biological_process | response to immobilization stress |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046836 | biological_process | glycolipid transport |
| A | 0051861 | molecular_function | glycolipid binding |
| A | 0120009 | biological_process | intermembrane lipid transfer |
| A | 0120013 | molecular_function | lipid transfer activity |
| A | 1902387 | molecular_function | ceramide 1-phosphate binding |
| A | 1902388 | molecular_function | ceramide 1-phosphate transfer activity |
| A | 1902389 | biological_process | ceramide 1-phosphate transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE CIS A 301 |
| Chain | Residue |
| A | PHE34 |
| A | HIS140 |
| A | VAL144 |
| A | LEU165 |
| A | PHE183 |
| A | TYR187 |
| A | TYR207 |
| A | HOH401 |
| A | HOH414 |
| A | HOH415 |
| A | HOH437 |
| A | PRO40 |
| A | HOH446 |
| A | HOH552 |
| A | PRO44 |
| A | ILE45 |
| A | ASN52 |
| A | ALA93 |
| A | TRP96 |
| A | PHE103 |
| A | PHE107 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15329726, ECO:0007744|PDB:1SX6 |
| Chain | Residue | Details |
| A | VAL48 | |
| A | HIS140 | |
| A | TYR207 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:P68266 |
| Chain | Residue | Details |
| A | ALA2 |
