3Q22
X-ray crystal structure of the N4 mini-VRNAP and P2_7a promoter transcription initiation complex with GTP and Magnesium: substrate complex I
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GTP A 1107 |
| Chain | Residue |
| A | ARG424 |
| C | DC5 |
| C | DA6 |
| A | LYS437 |
| A | ARG440 |
| A | ILE949 |
| A | PHE950 |
| A | ASP951 |
| A | GTP1108 |
| A | HOH1222 |
| A | HOH1371 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE GTP A 1108 |
| Chain | Residue |
| A | ARG424 |
| A | GLY560 |
| A | THR562 |
| A | ASN563 |
| A | GLY564 |
| A | PRO565 |
| A | TYR612 |
| A | ARG666 |
| A | LYS670 |
| A | ASN671 |
| A | TYR678 |
| A | ASP951 |
| A | GTP1107 |
| A | MG1110 |
| A | HOH1160 |
| A | HOH1261 |
| A | HOH1273 |
| A | HOH1371 |
| A | HOH1431 |
| A | HOH1531 |
| C | DC4 |
| C | DC5 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2HP A 1109 |
| Chain | Residue |
| A | GLN469 |
| A | ILE473 |
| A | LYS474 |
| A | VAL475 |
| A | HIS476 |
| A | HOH1176 |
| A | HOH1387 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 1110 |
| Chain | Residue |
| A | ASP559 |
| A | GLY560 |
| A | ASP951 |
| A | GTP1108 |
| site_id | AC5 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE GTP B 1107 |
| Chain | Residue |
| B | ARG424 |
| B | GLY560 |
| B | THR562 |
| B | ASN563 |
| B | GLY564 |
| B | TYR612 |
| B | ARG666 |
| B | LYS670 |
| B | ASN671 |
| B | ILE675 |
| B | TYR678 |
| B | ASP951 |
| B | MG1109 |
| B | HOH1521 |
| B | HOH1528 |
| B | HOH1794 |
| B | HOH1869 |
| B | HOH1994 |
| B | HOH2110 |
| D | DC4 |
| D | DC5 |
| D | GTP26 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2HP B 1108 |
| Chain | Residue |
| B | GLN469 |
| B | ILE473 |
| B | LYS474 |
| B | VAL475 |
| B | HIS476 |
| B | HOH1507 |
| B | HOH1795 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 1109 |
| Chain | Residue |
| B | ASP559 |
| B | GLY560 |
| B | ASP951 |
| B | GTP1107 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GTP D 26 |
| Chain | Residue |
| B | ARG424 |
| B | LYS437 |
| B | PHE950 |
| B | ASP951 |
| B | GTP1107 |
| B | HOH1528 |
| B | HOH1994 |
| D | DC5 |
| D | DA6 |
| D | HOH59 |
| D | HOH91 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 22 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21321236","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23235152","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
