Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE 03Q A 1 |
| Chain | Residue |
| A | HOH22 |
| A | LEU785 |
| A | LEU796 |
| A | THR798 |
| A | GLN799 |
| A | LEU800 |
| A | MET801 |
| A | ARG849 |
| A | ASN850 |
| A | LEU852 |
| A | THR862 |
| A | LEU726 |
| A | ASP863 |
| A | PHE864 |
| A | GLY729 |
| A | VAL734 |
| A | ALA751 |
| A | LYS753 |
| A | GLU770 |
| A | MET774 |
| A | SER783 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 03Q B 2 |
| Chain | Residue |
| B | HOH59 |
| B | LEU726 |
| B | VAL734 |
| B | ALA751 |
| B | LYS753 |
| B | GLU770 |
| B | ALA771 |
| B | MET774 |
| B | SER783 |
| B | LEU785 |
| B | LEU796 |
| B | THR798 |
| B | GLN799 |
| B | MET801 |
| B | ARG849 |
| B | ASN850 |
| B | LEU852 |
| B | THR862 |
| B | ASP863 |
| B | PHE1004 |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DDDMGDLVDaeEY |
| Chain | Residue | Details |
| A | ASP1011-TYR1023 | |
| site_id | PS00107 |
| Number of Residues | 28 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGSGAFGTVYkGiwipdgenvkip......VAIK |
| Chain | Residue | Details |
| A | LEU726-LYS753 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. LVHrDLAARNVLV |
| Chain | Residue | Details |
| A | LEU841-VAL853 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"32381043","evidenceCode":"ECO:0000305"}]} |
