3PEP

REVISED 2.3 ANGSTROMS STRUCTURE OF PORCINE PEPSIN. EVIDENCE FOR A FLEXIBLE SUBDOMAIN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004190	molecular_function	aspartic-type endopeptidase activity
A	0006508	biological_process	proteolysis

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EOH A 901

Chain	Residue
A	GLU13
A	TYR14
A	THR216
A	ASP303
A	HOH757

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EOH A 902

Chain	Residue
A	THR74
A	HOH694

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Functional Information from PROSITE/UniProt

site_id	PS00141
Number of Residues	12
Details	ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VIFDTGSSNLWV

Chain	Residue	Details
A	VAL29-VAL40
A	ALA212-GLY223

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10094, ECO:0000269|PubMed:1097438, ECO:0000269|PubMed:4897201

Chain	Residue	Details
A	ASP32
A	ASP215

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P03954

Chain	Residue	Details
A	SER68

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