3OLB

Poliovirus polymerase elongation complex with 2',3'-dideoxy-ctp

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003968	molecular_function	RNA-dependent RNA polymerase activity
A	0006351	biological_process	DNA-templated transcription
A	0039694	biological_process	viral RNA genome replication
E	0003723	molecular_function	RNA binding
E	0003968	molecular_function	RNA-dependent RNA polymerase activity
E	0006351	biological_process	DNA-templated transcription
E	0039694	biological_process	viral RNA genome replication
I	0003723	molecular_function	RNA binding
I	0003968	molecular_function	RNA-dependent RNA polymerase activity
I	0006351	biological_process	DNA-templated transcription
I	0039694	biological_process	viral RNA genome replication
M	0003723	molecular_function	RNA binding
M	0003968	molecular_function	RNA-dependent RNA polymerase activity
M	0006351	biological_process	DNA-templated transcription
M	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 2001

Chain	Residue
A	HIS270
A	HIS272
A	CYS281

---

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE DCT A 4004

Chain	Residue
A	HOH893
A	HOH894
A	HOH975
A	HOH977
B	G600
C	A701
A	LYS159
A	ARG163
A	LYS167
A	ARG174
A	ASP238
A	ASP328

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA A 6008

Chain	Residue
A	PRO202
A	ASP213
A	PHE217

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA A 6032

Chain	Residue
A	TYR313
A	TYR334
A	HIS336

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 2002

Chain	Residue
E	HIS270
E	HIS272
E	CYS281
E	IPA6027

---

site_id	AC6
Number of Residues	16
Details	BINDING SITE FOR RESIDUE DCT E 4003

Chain	Residue
E	LYS159
E	ARG163
E	LYS167
E	ARG174
E	ASP238
E	ASP328
E	HOH502
E	HOH656
E	HOH781
E	HOH953
E	HOH954
E	HOH956
E	HOH957
F	G600
G	A701
G	HOH958

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IPA E 6007

Chain	Residue
E	CYS212
E	ASP213
E	LEU216
E	PHE217

---

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE IPA E 6010

Chain	Residue
E	SER400
E	TRP403
E	THR404
E	LYS405
E	HIS413
E	HOH1005
G	G698
G	A699

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IPA E 6027

Chain	Residue
E	HIS272
E	ZN2002

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IPA E 6028

Chain	Residue
E	TYR313
E	HIS336

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN I 2003

Chain	Residue
I	HIS270
I	HIS272
I	CYS281
I	HOH675

---

site_id	BC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE DCT I 4002

Chain	Residue
I	LYS159
I	ARG163
I	ARG174
I	ASP328
I	HOH549
I	HOH938
I	HOH939
I	HOH941
I	HOH985
J	G600
K	A701

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IPA I 6015

Chain	Residue
I	GLU227
I	VAL366
I	THR367
I	TRP368

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IPA I 6023

Chain	Residue
I	TYR334
I	HIS336
I	GLU337
I	VAL338

---

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE IPA I 6026

Chain	Residue
I	VAL338
I	ALA340
I	PHE363
I	GLU364
I	HOH489
I	HOH505
I	HOH847

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN M 2004

Chain	Residue
M	HIS270
M	HIS272
M	CYS281
M	HOH478

---

site_id	BC8
Number of Residues	12
Details	BINDING SITE FOR RESIDUE DCT M 4001

Chain	Residue
M	HOH922
N	G600
O	A701
O	HOH921
M	LYS159
M	ARG163
M	LYS167
M	ARG174
M	ASP238
M	ASP328
M	HOH817
M	HOH831

---

site_id	BC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE IPA M 6025

Chain	Residue
M	ALA357
M	SER360
M	THR362
M	GLU364
M	HOH604

---

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA M 6031

Chain	Residue
M	TYR313
M	HIS336
M	GLU337

---

site_id	CC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE IPA O 6009

Chain	Residue
M	SER400
M	TRP403
M	THR404
M	HIS413
O	G698
O	A699

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