Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3OG6

The crystal structure of human interferon lambda 1 complexed with its high affinity receptor in space group P212121

Functional Information from GO Data
ChainGOidnamespacecontents
A0002829biological_processnegative regulation of type 2 immune response
A0005102molecular_functionsignaling receptor binding
A0005125molecular_functioncytokine activity
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0007259biological_processcell surface receptor signaling pathway via JAK-STAT
A0008285biological_processnegative regulation of cell population proliferation
A0032002cellular_componentinterleukin-28 receptor complex
A0032003molecular_functioninterleukin-28 receptor binding
A0032696biological_processnegative regulation of interleukin-13 production
A0032714biological_processnegative regulation of interleukin-5 production
A0032729biological_processpositive regulation of type II interferon production
A0038196biological_processtype III interferon-mediated signaling pathway
A0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
A0043381biological_processnegative regulation of memory T cell differentiation
A0045087biological_processinnate immune response
A0045345biological_processpositive regulation of MHC class I biosynthetic process
A0045581biological_processnegative regulation of T cell differentiation
A0045892biological_processnegative regulation of DNA-templated transcription
A0045893biological_processpositive regulation of DNA-templated transcription
A0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
A0050778biological_processpositive regulation of immune response
A0051607biological_processdefense response to virus
A0098586biological_processcellular response to virus
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:20934432
ChainResidueDetails
BASN9
BASN16
BASN122

site_idSWS_FT_FI2
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
BASN149

222926

PDB entries from 2024-07-24

PDB statisticsPDBj update infoContact PDBjnumon