Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1 |
| Chain | Residue |
| A | PHE130 |
| A | ALA132 |
| A | ILE163 |
| A | GLN165 |
| A | ARG230 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 2 |
| Chain | Residue |
| A | GLU26 |
| A | TRP27 |
| A | HOH649 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO A 3 |
| Chain | Residue |
| A | GLU24 |
| A | GLY25 |
| A | GLU26 |
| A | TRP27 |
| A | PRO28 |
| A | LEU70 |
| A | HIS71 |
| A | LEU155 |
| A | HOH384 |
| A | ASP23 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 4 |
| Chain | Residue |
| A | HIS143 |
| A | HOH382 |
| C | GLN53 |
| C | HOH360 |
| C | HOH479 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 6 |
| Chain | Residue |
| A | HIS91 |
| A | PHE93 |
| A | PHE234 |
| A | TRP237 |
| A | HOH468 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 7 |
| Chain | Residue |
| A | HIS57 |
| A | CYS58 |
| A | ILE60 |
| A | TYR60 |
| B | ARG100 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA A 245 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA A 246 |
| Chain | Residue |
| A | TRP141 |
| A | GLY193 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 215 |
| Chain | Residue |
| B | GLY100 |
| B | TYR100 |
| B | TYR100 |
| B | HOH294 |
| C | TYR96 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 216 |
| Chain | Residue |
| B | LYS19 |
| B | SER21 |
| B | TYR79 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 217 |
| Chain | Residue |
| B | HOH318 |
| C | THR5 |
| C | GLN6 |
| C | PRO7 |
| C | HOH395 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 10 |
| Chain | Residue |
| B | THR191 |
| C | PRO141 |
| C | GLN199 |
| C | HOH263 |
| C | HOH264 |
| C | HOH537 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA C 213 |
| Chain | Residue |
| C | VAL146 |
| C | GLU161 |
| C | SER177 |
| C | HOH524 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLS |
| Chain | Residue | Details |
| A | ASP189-SER200 | |
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| C | TYR192-HIS198 | |
| B | TYR194-HIS200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN164 | |
