3M4C

A Zn-mediated tetrahedral protein lattice cage encapsulating a microperoxidase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0009055	molecular_function	electron transfer activity
A	0020037	molecular_function	heme binding
A	0022900	biological_process	electron transport chain
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding
B	0005506	molecular_function	iron ion binding
B	0009055	molecular_function	electron transfer activity
B	0020037	molecular_function	heme binding
B	0022900	biological_process	electron transport chain
B	0042597	cellular_component	periplasmic space
B	0046872	molecular_function	metal ion binding
C	0005506	molecular_function	iron ion binding
C	0009055	molecular_function	electron transfer activity
C	0020037	molecular_function	heme binding
C	0022900	biological_process	electron transport chain
C	0042597	cellular_component	periplasmic space
C	0046872	molecular_function	metal ion binding
D	0005506	molecular_function	iron ion binding
D	0009055	molecular_function	electron transfer activity
D	0020037	molecular_function	heme binding
D	0022900	biological_process	electron transport chain
D	0042597	cellular_component	periplasmic space
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 107

Chain	Residue
A	ALA1
A	ASP39
A	HIS77
A	HOH228

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 108

Chain	Residue
A	GLU8
A	ASP12
C	GLU8
C	ASP12

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 109

Chain	Residue
A	HIS63
A	ACT151
A	HOH259
A	HIS59

---

site_id	AC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEM A 150

Chain	Residue
A	GLU4
A	MET7
A	ASN11
A	PRO45
A	PRO46
A	PHE61
A	PHE65
A	CYS98
A	CYS101
A	HIS102
A	TYR105
A	ARG106
A	HOH221
A	HOH224
A	HOH229
A	HOH292
C	GLN103

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT A 151

Chain	Residue
A	ASP54
A	HIS59
A	ARG62
A	HIS63
A	CYS67
A	ZN109
A	HOH283

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 107

Chain	Residue
B	ALA1
B	ASP39
B	HOH220
D	HIS77

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 108

Chain	Residue
B	GLU8
B	ASP12
D	GLU8
D	ASP12

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 109

Chain	Residue
B	ASP54
B	HIS59
B	HOH247
D	HIS63
D	ACT107

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 110

Chain	Residue
B	HIS63
B	ACT151
C	ASP54
C	HIS59

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 111

Chain	Residue
B	HIS77
C	ALA1
C	ASP39
C	HOH209

---

site_id	BC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE HEM B 150

Chain	Residue
B	GLU4
B	MET7
B	PRO45
B	PRO46
B	PHE61
B	PHE65
B	CYS98
B	CYS101
B	HIS102
B	TYR105
B	ARG106
B	HOH293

---

site_id	BC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ACT B 151

Chain	Residue
B	HIS63
B	CYS67
B	ZN110
B	HOH202
C	PRO53
C	ASP54
C	HIS59
C	ARG62

---

site_id	BC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEM C 150

Chain	Residue
C	GLU4
C	MET7
C	ASN11
C	PRO45
C	PRO46
C	PHE61
C	PHE65
C	CYS98
C	CYS101
C	HIS102
C	ARG106
C	ARG106
C	HOH213
C	HOH221
C	HOH224
C	HOH280
C	HOH292

---

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT D 107

Chain	Residue
D	HIS63
D	CYS67
B	PRO53
B	ASP54
B	HIS59
B	ARG62
B	ZN109

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 108

Chain	Residue
C	HIS63
D	ASP54
D	HIS59
D	ACT151

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 109

Chain	Residue
C	HIS77
D	ALA1
D	ASP39
D	HOH225

---

site_id	BC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT D 151

Chain	Residue
C	HIS63
C	CYS67
D	PRO53
D	ASP54
D	HIS59
D	ARG62
D	ZN108

---

site_id	BC9
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEM D 150

Chain	Residue
D	GLU4
D	MET7
D	PRO45
D	PRO46
D	PHE61
D	PHE65
D	CYS98
D	CYS101
D	HIS102
D	TYR105
D	ARG106
D	HOH213
D	HOH233
D	HOH274
D	HOH298

---

site_id	CC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE HEM E 150

Chain	Residue
B	THR31
B	ALA34
B	ALA38
B	TRP66
B	HIS73
B	ASN80
C	ALA38
C	ASP39
C	TRP41
E	THR97
E	CYS98
E	CYS101
E	HIS102
E	HOH202
E	HOH204
E	HOH205

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	88
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	52
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"description":"axial binding residue"}

Chain

Residue

Details

---