3LDB

Structure of JMJD6 complexd with ALPHA-KETOGLUTARATE and Fab Fragment.

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 335

Chain	Residue
A	ASP50
A	GLN53
A	GLU58
A	ARG62
C	SER54

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL A 336

Chain	Residue
A	ASP279
A	THR280

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 337

Chain	Residue
A	LYS6
A	ILE9
A	GLU119
A	SER123
A	MET1
A	SER5

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 338

Chain	Residue
A	ARG95
A	ASN96
A	LYS115

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL B 221

Chain	Residue
A	GLU334
B	ARG114

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 339

Chain	Residue
A	ASN237
A	PRO241
C	SER31
C	ASN53
C	TYR100

---

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 C 222

Chain	Residue
C	ARG71

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 340

Chain	Residue
A	ASN96
A	GLN97
A	LYS142

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 341

Chain	Residue
A	SER109
A	LYS111
A	SER136

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 342

Chain	Residue
A	LEU147
A	ARG173

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 343

Chain	Residue
A	THR221
A	ARG222
A	GLN229

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 222

Chain	Residue
B	GLN48
B	SER49
B	LYS51
C	GLN110

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 344

Chain	Residue
A	GLN97
A	HIS140
A	LYS142
A	ARG143

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 345

Chain	Residue
A	ARG8
A	LYS113
A	LYS115
A	TYR116

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 346

Chain	Residue
A	GLY165
A	GLU166
A	LYS167
A	ARG168

---

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 347

Chain	Residue
A	PRO190
A	LEU191
A	LYS300

---

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 348

Chain	Residue
A	ARG215
A	GLU216

---

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 349

Chain	Residue
A	ARG310
A	ARG314

---

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 350

Chain	Residue
A	ARG305
A	PRO306
A	LYS307
A	LEU308

---

site_id	CC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 B 223

Chain	Residue
B	LYS18
B	THR20
B	SER71
B	GLY72
B	ASP76
B	THR78
B	THR80

---

site_id	CC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SO4 C 223

Chain	Residue
B	LEU166
B	GLN167
B	SER168
B	SER182
B	THR184
C	PRO174
C	VAL176
C	SER183
C	LEU184
C	SER185

---

site_id	CC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 C 224

Chain	Residue
C	GLN81

---

site_id	CC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 351

Chain	Residue
A	TYR313
A	ASP328
A	ASP331

---

site_id	CC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 224

Chain	Residue
B	GLN43
B	LYS51
B	LEU53
B	PRO65

---

site_id	CC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE AKG A 600

Chain	Residue
A	TRP174
A	THR184
A	ASN197
A	THR285
A	FE601

---

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE A 601

Chain	Residue
A	HIS187
A	ASP189
A	HIS273
A	AKG600

---

site_id	CC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HG A 352

Chain	Residue
A	TRP206
A	CYS207

---

site_id	DC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HG A 353

Chain	Residue
A	MET112
A	CYS101

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEVTH

Chain	Residue	Details
B	TYR198-HIS204

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	164
Details	Domain: {"description":"JmjC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00538","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Motif: {"description":"Nuclear localization signal 1","evidences":[{"source":"PubMed","id":"14729065","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Motif: {"description":"Nuclear localization signal 2","evidences":[{"source":"PubMed","id":"14729065","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Motif: {"description":"Nuclear localization signal 3","evidences":[{"source":"PubMed","id":"14729065","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Motif: {"description":"Nuclear localization signal 4","evidences":[{"source":"PubMed","id":"14729065","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20679243","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---