3LBL

Structure of human MDM2 protein in complex with Mi-63-analog

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0043066	biological_process	negative regulation of apoptotic process
A	0051726	biological_process	regulation of cell cycle
C	0005634	cellular_component	nucleus
C	0043066	biological_process	negative regulation of apoptotic process
C	0051726	biological_process	regulation of cell cycle
E	0005634	cellular_component	nucleus
E	0043066	biological_process	negative regulation of apoptotic process
E	0051726	biological_process	regulation of cell cycle

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MI6 A 1

Chain	Residue
A	LEU54
A	GLY58
A	MET62
A	PHE86
A	VAL93
A	HIS96
A	ILE99
A	HOH152

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site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE MI6 C 1

Chain	Residue
C	LEU54
C	GLY58
C	ILE61
C	TYR67
C	GLU69
C	PHE86
C	VAL93
C	HIS96
C	ILE99
C	TYR100
A	ARG97

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site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MI6 E 1

Chain	Residue
E	LEU54
E	MET62
E	PHE86
E	VAL93
E	HIS96
E	ILE99
E	TYR100
E	HOH260

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	83
Details	Domain: {"description":"SWIB/MDM2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01273","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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