Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0008398 | molecular_function | sterol 14-demethylase activity |
A | 0016020 | cellular_component | membrane |
A | 0016126 | biological_process | sterol biosynthetic process |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 22 |
Details | BINDING SITE FOR RESIDUE HEM A 500 |
Chain | Residue |
A | ARG124 |
A | LEU356 |
A | VAL359 |
A | ARG361 |
A | GLY414 |
A | PHE415 |
A | GLY416 |
A | VAL419 |
A | HIS420 |
A | LYS421 |
A | CYS422 |
A | LEU127 |
A | ILE423 |
A | GLY424 |
A | TPF501 |
A | LEU134 |
A | ALA288 |
A | ALA291 |
A | GLY292 |
A | THR295 |
A | THR299 |
A | PRO355 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE TPF A 501 |
Chain | Residue |
A | TYR116 |
A | PHE290 |
A | ALA291 |
A | THR295 |
A | LEU356 |
A | HEM500 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGaGVHKCIG |
Chain | Residue | Details |
A | PHE415-GLY424 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | CYS422 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1akd |
Chain | Residue | Details |
A | HIS294 | |
A | THR295 | |