Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GLU A 263 |
| Chain | Residue |
| A | TYR61 |
| A | TYR220 |
| A | HOH269 |
| A | HOH278 |
| A | HOH338 |
| A | PRO89 |
| A | LEU90 |
| A | THR91 |
| A | ARG96 |
| A | GLY141 |
| A | SER142 |
| A | THR143 |
| A | GLU193 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ZK1 B 263 |
| Chain | Residue |
| B | GLU13 |
| B | TYR16 |
| B | TYR61 |
| B | PRO89 |
| B | LEU90 |
| B | THR91 |
| B | ARG96 |
| B | GLY141 |
| B | SER142 |
| B | THR174 |
| B | GLU193 |
| B | MET196 |
| B | TYR220 |
| B | HOH294 |
| B | HOH418 |
| B | HOH429 |
| B | HOH504 |
| B | HOH508 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 264 |
| Chain | Residue |
| B | HIS23 |
| B | LYS144 |
| B | ARG148 |
| B | TRP159 |
| B | ARG163 |
| B | HOH368 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE LY7 A 264 |
| Chain | Residue |
| A | ILE92 |
| A | PRO105 |
| A | SER108 |
| A | LYS218 |
| A | GLY219 |
| A | SER242 |
| A | LEU247 |
| A | HOH447 |
| B | LYS104 |
| B | PRO105 |
| B | MET107 |
| B | SER108 |
| B | LEU239 |
| B | SER242 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 265 |
| Chain | Residue |
| A | SER140 |
| A | LYS144 |
| A | ARG148 |
| A | HOH315 |
| A | HOH324 |
| A | HOH330 |
| A | HOH393 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | PRO89 | |
| B | MET162 | |
| B | ARG163 | |
| B | GLY213 | |
| A | THR91 | |
| A | ARG96 | |
| A | MET162 | |
| A | ARG163 | |
| A | GLY213 | |
| B | PRO89 | |
| B | THR91 | |
| B | ARG96 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ARG64 | |
| A | SER168 | |
| A | GLU260 | |
| B | ARG64 | |
| B | SER168 | |
| B | GLU260 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | GLY141 | |
| B | GLY141 | |
| Chain | Residue | Details |
| A | PHE170 | |
| B | PHE170 | |
| Chain | Residue | Details |
| A | LYS204 | |
| B | LYS204 | |
