Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| C | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| C | 0007601 | biological_process | visual perception |
| C | 0030553 | molecular_function | cGMP binding |
| D | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| D | 0007601 | biological_process | visual perception |
| D | 0030553 | molecular_function | cGMP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 899 |
| Chain | Residue |
| A | HIS617 |
| A | HIS653 |
| A | ASP654 |
| A | ASP764 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN B 899 |
| Chain | Residue |
| B | ASP764 |
| B | HOH12 |
| B | HOH18 |
| B | HIS617 |
| B | HIS653 |
| B | ASP654 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 900 |
| Chain | Residue |
| A | HOH5 |
| A | ASP654 |
| A | GLU682 |
| A | THR723 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IBM A 901 |
| Chain | Residue |
| A | HIS613 |
| A | LEU765 |
| A | GLN817 |
| A | PHE820 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE IBM A 902 |
| Chain | Residue |
| A | LEU693 |
| A | GLN699 |
| A | LEU701 |
| A | SER702 |
| A | LEU704 |
| A | TYR709 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE IBM A 903 |
| Chain | Residue |
| A | ASP687 |
| A | LEU690 |
| B | ALA545 |
| B | ALA546 |
| B | VAL547 |
| B | HIS592 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG B 900 |
| Chain | Residue |
| B | HOH11 |
| B | HOH12 |
| B | HOH15 |
| B | HOH16 |
| B | ASP654 |
| B | GLU682 |
| B | THR723 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IBM B 901 |
| Chain | Residue |
| B | LEU765 |
| B | VAL782 |
| B | PHE786 |
| B | GLN817 |
| B | PHE820 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE IBM B 902 |
| Chain | Residue |
| B | GLN699 |
| B | LEU701 |
| B | SER702 |
| B | LEU704 |
| B | ILE706 |
| B | TYR709 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHrGvnNsY |
| Chain | Residue | Details |
| A | HIS653-TYR664 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12955149","evidenceCode":"ECO:0000269"}]} |
