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3J1O

Cryo-EM map of a yeast minimal preinitiation complex interacting with the Mediator Head module

Functional Information from GO Data
ChainGOidnamespacecontents
H0000122biological_processnegative regulation of transcription by RNA polymerase II
H0001097molecular_functionTFIIH-class transcription factor complex binding
H0003712molecular_functiontranscription coregulator activity
H0003713molecular_functiontranscription coactivator activity
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0006357biological_processregulation of transcription by RNA polymerase II
H0016592cellular_componentmediator complex
H0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
H0045944biological_processpositive regulation of transcription by RNA polymerase II
H0051123biological_processRNA polymerase II preinitiation complex assembly
H0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
H0070847cellular_componentcore mediator complex
I0003712molecular_functiontranscription coregulator activity
I0006357biological_processregulation of transcription by RNA polymerase II
I0016592cellular_componentmediator complex
J0000122biological_processnegative regulation of transcription by RNA polymerase II
J0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
J0003677molecular_functionDNA binding
J0003712molecular_functiontranscription coregulator activity
J0003714molecular_functiontranscription corepressor activity
J0005515molecular_functionprotein binding
J0005634cellular_componentnucleus
J0006357biological_processregulation of transcription by RNA polymerase II
J0016592cellular_componentmediator complex
J0017025molecular_functionTBP-class protein binding
J0030674molecular_functionprotein-macromolecule adaptor activity
J0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
J0045944biological_processpositive regulation of transcription by RNA polymerase II
J0051123biological_processRNA polymerase II preinitiation complex assembly
J0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
J0070847cellular_componentcore mediator complex
K0003674molecular_functionmolecular_function
K0003712molecular_functiontranscription coregulator activity
K0005515molecular_functionprotein binding
K0005634cellular_componentnucleus
K0006357biological_processregulation of transcription by RNA polymerase II
K0016592cellular_componentmediator complex
K0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
K0045944biological_processpositive regulation of transcription by RNA polymerase II
K0051123biological_processRNA polymerase II preinitiation complex assembly
K0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
K0070847cellular_componentcore mediator complex
L0000979molecular_functionRNA polymerase II core promoter sequence-specific DNA binding
L0001113biological_processtranscription open complex formation at RNA polymerase II promoter
L0003712molecular_functiontranscription coregulator activity
L0003713molecular_functiontranscription coactivator activity
L0005515molecular_functionprotein binding
L0005634cellular_componentnucleus
L0006357biological_processregulation of transcription by RNA polymerase II
L0006369biological_processtermination of RNA polymerase II transcription
L0016592cellular_componentmediator complex
L0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
L0034605biological_processcellular response to heat
L0045944biological_processpositive regulation of transcription by RNA polymerase II
L0051123biological_processRNA polymerase II preinitiation complex assembly
L0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
L0070847cellular_componentcore mediator complex
M0001094molecular_functionTFIID-class transcription factor complex binding
M0003712molecular_functiontranscription coregulator activity
M0003713molecular_functiontranscription coactivator activity
M0005515molecular_functionprotein binding
M0005634cellular_componentnucleus
M0006357biological_processregulation of transcription by RNA polymerase II
M0010688biological_processnegative regulation of ribosomal protein gene transcription by RNA polymerase II
M0016592cellular_componentmediator complex
M0019904molecular_functionprotein domain specific binding
M0031669biological_processcellular response to nutrient levels
M0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
M0032991cellular_componentprotein-containing complex
M0045944biological_processpositive regulation of transcription by RNA polymerase II
M0051123biological_processRNA polymerase II preinitiation complex assembly
M0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
M0070847cellular_componentcore mediator complex
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylserine => ECO:0007744|PubMed:22814378
ChainResidueDetails
KSER2

222926

PDB entries from 2024-07-24

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