3J1O

Cryo-EM map of a yeast minimal preinitiation complex interacting with the Mediator Head module

Functional Information from GO Data

Chain	GOid	namespace	contents
H	0000122	biological_process	negative regulation of transcription by RNA polymerase II
H	0001097	molecular_function	TFIIH-class transcription factor complex binding
H	0003712	molecular_function	transcription coregulator activity
H	0003713	molecular_function	transcription coactivator activity
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0006351	biological_process	DNA-templated transcription
H	0006357	biological_process	regulation of transcription by RNA polymerase II
H	0016592	cellular_component	mediator complex
H	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
H	0045944	biological_process	positive regulation of transcription by RNA polymerase II
H	0051123	biological_process	RNA polymerase II preinitiation complex assembly
H	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
H	0070847	cellular_component	core mediator complex
I	0003712	molecular_function	transcription coregulator activity
I	0006357	biological_process	regulation of transcription by RNA polymerase II
I	0016592	cellular_component	mediator complex
J	0000122	biological_process	negative regulation of transcription by RNA polymerase II
J	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
J	0003677	molecular_function	DNA binding
J	0003712	molecular_function	transcription coregulator activity
J	0003714	molecular_function	transcription corepressor activity
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0006351	biological_process	DNA-templated transcription
J	0006357	biological_process	regulation of transcription by RNA polymerase II
J	0016592	cellular_component	mediator complex
J	0017025	molecular_function	TBP-class protein binding
J	0030674	molecular_function	protein-macromolecule adaptor activity
J	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
J	0045944	biological_process	positive regulation of transcription by RNA polymerase II
J	0051123	biological_process	RNA polymerase II preinitiation complex assembly
J	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
J	0070847	cellular_component	core mediator complex
K	0003674	molecular_function	molecular_function
K	0003712	molecular_function	transcription coregulator activity
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0006351	biological_process	DNA-templated transcription
K	0006357	biological_process	regulation of transcription by RNA polymerase II
K	0016592	cellular_component	mediator complex
K	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
K	0045944	biological_process	positive regulation of transcription by RNA polymerase II
K	0051123	biological_process	RNA polymerase II preinitiation complex assembly
K	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
K	0070847	cellular_component	core mediator complex
L	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
L	0001113	biological_process	transcription open complex formation at RNA polymerase II promoter
L	0003712	molecular_function	transcription coregulator activity
L	0003713	molecular_function	transcription coactivator activity
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0006351	biological_process	DNA-templated transcription
L	0006357	biological_process	regulation of transcription by RNA polymerase II
L	0006369	biological_process	termination of RNA polymerase II transcription
L	0016592	cellular_component	mediator complex
L	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
L	0034605	biological_process	cellular response to heat
L	0045944	biological_process	positive regulation of transcription by RNA polymerase II
L	0051123	biological_process	RNA polymerase II preinitiation complex assembly
L	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
L	0070847	cellular_component	core mediator complex
M	0001094	molecular_function	TFIID-class transcription factor complex binding
M	0003712	molecular_function	transcription coregulator activity
M	0003713	molecular_function	transcription coactivator activity
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0006351	biological_process	DNA-templated transcription
M	0006357	biological_process	regulation of transcription by RNA polymerase II
M	0010688	biological_process	negative regulation of ribosomal protein gene transcription by RNA polymerase II
M	0016592	cellular_component	mediator complex
M	0019904	molecular_function	protein domain specific binding
M	0031669	biological_process	cellular response to nutrient levels
M	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
M	0032991	cellular_component	protein-containing complex
M	0045944	biological_process	positive regulation of transcription by RNA polymerase II
M	0051123	biological_process	RNA polymerase II preinitiation complex assembly
M	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
M	0070847	cellular_component	core mediator complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	26
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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