3HPG

Visna virus integrase (residues 1-219) in complex with LEDGF IBD: examples of open integrase dimer-dimer interfaces

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0008270	molecular_function	zinc ion binding
A	0015074	biological_process	DNA integration
B	0003676	molecular_function	nucleic acid binding
B	0008270	molecular_function	zinc ion binding
B	0015074	biological_process	DNA integration
C	0003676	molecular_function	nucleic acid binding
C	0008270	molecular_function	zinc ion binding
C	0015074	biological_process	DNA integration
D	0003676	molecular_function	nucleic acid binding
D	0008270	molecular_function	zinc ion binding
D	0015074	biological_process	DNA integration
E	0003676	molecular_function	nucleic acid binding
E	0008270	molecular_function	zinc ion binding
E	0015074	biological_process	DNA integration
F	0003676	molecular_function	nucleic acid binding
F	0008270	molecular_function	zinc ion binding
F	0015074	biological_process	DNA integration

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 220

Chain	Residue
A	HIS12
A	HIS16
A	CYS40
A	CYS43

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 220

Chain	Residue
B	HIS12
B	HIS16
B	CYS40
B	CYS43

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 220

Chain	Residue
C	HIS16
C	CYS40
C	CYS43
C	HIS12

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 220

Chain	Residue
D	HIS12
D	HIS16
D	CYS40
D	CYS43

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 220

Chain	Residue
E	HIS12
E	HIS16
E	CYS40
E	CYS43

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 220

Chain	Residue
F	HIS12
F	HIS16
F	CYS40
F	CYS43

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00450","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00457","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	160
Details	Domain: {"description":"Integrase catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00457","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	123
Details	Zinc finger: {"description":"Integrase-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00450","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	24
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---