3HPG

Visna virus integrase (residues 1-219) in complex with LEDGF IBD: examples of open integrase dimer-dimer interfaces

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0008270	molecular_function	zinc ion binding
A	0015074	biological_process	DNA integration
B	0003676	molecular_function	nucleic acid binding
B	0008270	molecular_function	zinc ion binding
B	0015074	biological_process	DNA integration
C	0003676	molecular_function	nucleic acid binding
C	0008270	molecular_function	zinc ion binding
C	0015074	biological_process	DNA integration
D	0003676	molecular_function	nucleic acid binding
D	0008270	molecular_function	zinc ion binding
D	0015074	biological_process	DNA integration
E	0003676	molecular_function	nucleic acid binding
E	0008270	molecular_function	zinc ion binding
E	0015074	biological_process	DNA integration
F	0003676	molecular_function	nucleic acid binding
F	0008270	molecular_function	zinc ion binding
F	0015074	biological_process	DNA integration

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 220

Chain	Residue
A	HIS12
A	HIS16
A	CYS40
A	CYS43

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 220

Chain	Residue
B	HIS12
B	HIS16
B	CYS40
B	CYS43

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 220

Chain	Residue
C	HIS16
C	CYS40
C	CYS43
C	HIS12

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 220

Chain	Residue
D	HIS12
D	HIS16
D	CYS40
D	CYS43

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 220

Chain	Residue
E	HIS12
E	HIS16
E	CYS40
E	CYS43

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 220

Chain	Residue
F	HIS12
F	HIS16
F	CYS40
F	CYS43

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
G	SER434
D	LEU160
D	GLY192
D	GLN212
E	LEU160
E	GLY192
E	GLN212
F	LEU160
F	GLY192
F	GLN212
H	SER434
I	SER434
J	SER434
K	SER434
L	SER434
C	LEU160
C	GLY192
C	GLN212

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