Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| A | 0010608 | biological_process | post-transcriptional regulation of gene expression |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0010608 | biological_process | post-transcriptional regulation of gene expression |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 074 A 348 |
| Chain | Residue |
| A | GLN116 |
| A | HIS194 |
| A | HIS195 |
| A | GLY281 |
| A | HIS282 |
| A | TRP304 |
| A | HOH422 |
| A | HOH481 |
| A | HOH588 |
| A | HOH595 |
| A | SER117 |
| A | GLY120 |
| A | SER121 |
| A | CYS122 |
| A | TRP123 |
| A | GLY164 |
| A | GLY165 |
| A | PRO167 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TRS A 1 |
| Chain | Residue |
| A | ASP150 |
| A | CYS154 |
| A | TYR173 |
| A | GLY178 |
| A | LEU179 |
| A | VAL180 |
| A | ASN228 |
| A | HOH424 |
| A | HOH590 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 2 |
| Chain | Residue |
| A | ALA114 |
| A | ASP115 |
| A | ALA148 |
| A | HOH399 |
| A | HOH451 |
| A | HOH534 |
| A | HOH581 |
| A | HOH589 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 5 |
| Chain | Residue |
| A | ALA256 |
| A | PHE257 |
| A | ASP258 |
| A | GLY324 |
| A | ASP327 |
| A | HOH362 |
| A | HOH490 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 349 |
| Chain | Residue |
| A | GLU88 |
| A | HOH566 |
| B | HOH16 |
| B | ARG250 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 074 B 348 |
| Chain | Residue |
| B | GLN116 |
| B | SER117 |
| B | GLY120 |
| B | SER121 |
| B | CYS122 |
| B | TRP123 |
| B | GLY164 |
| B | GLY165 |
| B | PRO167 |
| B | HIS194 |
| B | HIS195 |
| B | GLY281 |
| B | HIS282 |
| B | TRP304 |
| B | HOH445 |
| B | HOH504 |
| B | HOH532 |
| B | HOH612 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 1 |
| Chain | Residue |
| B | ALA114 |
| B | ASP115 |
| B | ALA148 |
| B | HOH394 |
| B | HOH414 |
| B | HOH428 |
| B | HOH528 |
| B | HOH546 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 350 |
| Chain | Residue |
| B | ALA256 |
| B | PHE257 |
| B | ASP258 |
| B | GLY324 |
| B | ASP327 |
| B | HOH621 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 3 |
| Chain | Residue |
| A | PHE98 |
| A | ASP99 |
| A | GLU102 |
| A | PHE248 |
| B | PRO93 |
| B | PRO95 |
| B | HOH437 |
| B | HOH538 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 4 |
| Chain | Residue |
| A | PRO93 |
| A | PRO95 |
| B | PHE98 |
| B | ASP99 |
| B | GLU102 |
| B | PHE248 |
| B | HOH436 |
| B | HOH589 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE LI B 349 |
| Chain | Residue |
| B | ASP220 |
| B | HOH547 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QSaCGSCWAvAA |
| Chain | Residue | Details |
| A | GLN116-ALA127 | |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. GGHAVRLVGWG |
| Chain | Residue | Details |
| A | GLY280-GLY290 | |
