3HDE

Crystal structure of full-length endolysin R21 from phage 21

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003796	molecular_function	lysozyme activity
A	0003824	molecular_function	catalytic activity
A	0009253	biological_process	peptidoglycan catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0016998	biological_process	cell wall macromolecule catabolic process
A	0020002	cellular_component	host cell plasma membrane
A	0031640	biological_process	killing of cells of another organism
A	0042742	biological_process	defense response to bacterium
B	0003796	molecular_function	lysozyme activity
B	0003824	molecular_function	catalytic activity
B	0009253	biological_process	peptidoglycan catabolic process
B	0016787	molecular_function	hydrolase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0016998	biological_process	cell wall macromolecule catabolic process
B	0020002	cellular_component	host cell plasma membrane
B	0031640	biological_process	killing of cells of another organism
B	0042742	biological_process	defense response to bacterium
C	0003796	molecular_function	lysozyme activity
C	0003824	molecular_function	catalytic activity
C	0009253	biological_process	peptidoglycan catabolic process
C	0016787	molecular_function	hydrolase activity
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0016998	biological_process	cell wall macromolecule catabolic process
C	0020002	cellular_component	host cell plasma membrane
C	0031640	biological_process	killing of cells of another organism
C	0042742	biological_process	defense response to bacterium
D	0003796	molecular_function	lysozyme activity
D	0003824	molecular_function	catalytic activity
D	0009253	biological_process	peptidoglycan catabolic process
D	0016787	molecular_function	hydrolase activity
D	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
D	0016998	biological_process	cell wall macromolecule catabolic process
D	0020002	cellular_component	host cell plasma membrane
D	0031640	biological_process	killing of cells of another organism
D	0042742	biological_process	defense response to bacterium

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	80
Details	Transmembrane: {"description":"Helical; Signal-anchor for type II membrane protein","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_04136","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19881499","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 206l

Chain	Residue	Details
A	ASP44
A	GLU35

---

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 206l

Chain	Residue	Details
B	ASP44
B	GLU35

---

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 206l

Chain	Residue	Details
C	ASP44
C	GLU35

---

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 206l

Chain	Residue	Details
D	ASP44
D	GLU35

---