3G8Q

A cytidine deaminase edits C-to-U in transfer RNAs in archaea

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0003723	molecular_function	RNA binding
A	0003824	molecular_function	catalytic activity
A	0006400	biological_process	tRNA modification
A	0008033	biological_process	tRNA processing
A	0008270	molecular_function	zinc ion binding
A	0016554	biological_process	cytidine to uridine editing
A	0016787	molecular_function	hydrolase activity
A	0016814	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0046872	molecular_function	metal ion binding
B	0000049	molecular_function	tRNA binding
B	0003723	molecular_function	RNA binding
B	0003824	molecular_function	catalytic activity
B	0006400	biological_process	tRNA modification
B	0008033	biological_process	tRNA processing
B	0008270	molecular_function	zinc ion binding
B	0016554	biological_process	cytidine to uridine editing
B	0016787	molecular_function	hydrolase activity
B	0016814	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0046872	molecular_function	metal ion binding
C	0000049	molecular_function	tRNA binding
C	0003723	molecular_function	RNA binding
C	0003824	molecular_function	catalytic activity
C	0006400	biological_process	tRNA modification
C	0008033	biological_process	tRNA processing
C	0008270	molecular_function	zinc ion binding
C	0016554	biological_process	cytidine to uridine editing
C	0016787	molecular_function	hydrolase activity
C	0016814	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0046872	molecular_function	metal ion binding
D	0000049	molecular_function	tRNA binding
D	0003723	molecular_function	RNA binding
D	0003824	molecular_function	catalytic activity
D	0006400	biological_process	tRNA modification
D	0008033	biological_process	tRNA processing
D	0008270	molecular_function	zinc ion binding
D	0016554	biological_process	cytidine to uridine editing
D	0016787	molecular_function	hydrolase activity
D	0016814	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 301

Chain	Residue
A	HIS44
A	GLU46
A	CYS67
A	CYS70
A	HOH326

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 301

Chain	Residue
B	HIS44
B	GLU46
B	CYS67
B	CYS70

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN C 301

Chain	Residue
C	HIS44
C	CYS67
C	CYS70

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 301

Chain	Residue
D	HIS44
D	CYS67
D	CYS70
D	HOH305

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA D 302

Chain	Residue
D	ASN17
D	GLY113
D	ASP115
D	HOH341
D	HOH342

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA C 302

Chain	Residue
C	ASP265
C	ARG270
C	SER272

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA A 302

Chain	Residue
A	LEU123
A	THR125
A	ARG189
A	ARG191

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA C 303

Chain	Residue
A	ASP257
C	ASP173
C	ASP175
C	HOH335

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA B 302

Chain	Residue
B	ASP41
B	ASP173
B	ASP175
B	HOH310

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA D 303

Chain	Residue
C	GLU183
D	GLU176
D	GLU179
D	HOH338

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA D 304

Chain	Residue
C	GLU179
D	GLU179
D	HOH336
D	HOH359

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton donor => ECO:0000250

Chain	Residue	Details
A	GLU46
B	GLU46
C	GLU46
D	GLU46

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:19407206

Chain	Residue	Details
A	HIS44
D	HIS44
D	CYS67
D	CYS70
A	CYS67
A	CYS70
B	HIS44
B	CYS67
B	CYS70
C	HIS44
C	CYS67
C	CYS70

---