Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3G3B

Structure of a lamprey variable lymphocyte receptor mutant in complex with a protein antigen

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0003796	molecular_function	lysozyme activity
B	0003824	molecular_function	catalytic activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005737	cellular_component	cytoplasm
B	0005783	cellular_component	endoplasmic reticulum
B	0008152	biological_process	metabolic process
B	0016231	molecular_function	beta-N-acetylglucosaminidase activity
B	0016787	molecular_function	hydrolase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0016998	biological_process	cell wall macromolecule catabolic process
B	0031640	biological_process	killing of cells of another organism
B	0042742	biological_process	defense response to bacterium
B	0042802	molecular_function	identical protein binding
B	0050829	biological_process	defense response to Gram-negative bacterium
B	0050830	biological_process	defense response to Gram-positive bacterium
B	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
D	0003796	molecular_function	lysozyme activity
D	0003824	molecular_function	catalytic activity
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0005737	cellular_component	cytoplasm
D	0005783	cellular_component	endoplasmic reticulum
D	0008152	biological_process	metabolic process
D	0016231	molecular_function	beta-N-acetylglucosaminidase activity
D	0016787	molecular_function	hydrolase activity
D	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
D	0016998	biological_process	cell wall macromolecule catabolic process
D	0031640	biological_process	killing of cells of another organism
D	0042742	biological_process	defense response to bacterium
D	0042802	molecular_function	identical protein binding
D	0050829	biological_process	defense response to Gram-negative bacterium
D	0050830	biological_process	defense response to Gram-positive bacterium
D	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
F	0003796	molecular_function	lysozyme activity
F	0003824	molecular_function	catalytic activity
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0005737	cellular_component	cytoplasm
F	0005783	cellular_component	endoplasmic reticulum
F	0008152	biological_process	metabolic process
F	0016231	molecular_function	beta-N-acetylglucosaminidase activity
F	0016787	molecular_function	hydrolase activity
F	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
F	0016998	biological_process	cell wall macromolecule catabolic process
F	0031640	biological_process	killing of cells of another organism
F	0042742	biological_process	defense response to bacterium
F	0042802	molecular_function	identical protein binding
F	0050829	biological_process	defense response to Gram-negative bacterium
F	0050830	biological_process	defense response to Gram-positive bacterium
F	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
H	0003796	molecular_function	lysozyme activity
H	0003824	molecular_function	catalytic activity
H	0005515	molecular_function	protein binding
H	0005576	cellular_component	extracellular region
H	0005615	cellular_component	extracellular space
H	0005737	cellular_component	cytoplasm
H	0005783	cellular_component	endoplasmic reticulum
H	0008152	biological_process	metabolic process
H	0016231	molecular_function	beta-N-acetylglucosaminidase activity
H	0016787	molecular_function	hydrolase activity
H	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
H	0016998	biological_process	cell wall macromolecule catabolic process
H	0031640	biological_process	killing of cells of another organism
H	0042742	biological_process	defense response to bacterium
H	0042802	molecular_function	identical protein binding
H	0050829	biological_process	defense response to Gram-negative bacterium
H	0050830	biological_process	defense response to Gram-positive bacterium
H	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism

Functional Information from PROSITE/UniProt

site_id	PS00128
Number of Residues	19
Details	GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC

Chain	Residue	Details
B	CYS76-CYS94

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE:

Chain	Residue	Details
B	GLU35
B	ASP52
D	GLU35
D	ASP52
F	GLU35
F	ASP52
H	GLU35
H	ASP52

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING:

Chain	Residue	Details
B	ASP101
D	ASP101
F	ASP101
H	ASP101

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
B	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
B	ASN46
B	ASP48
B	SER50
B	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
B	ASN59

site_id	MCSA2
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
D	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
D	ASN46
D	ASP48
D	SER50
D	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
D	ASN59

site_id	MCSA3
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
F	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
F	ASN46
F	ASP48
F	SER50
F	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
F	ASN59

site_id	MCSA4
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
H	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
H	ASN46
H	ASP48
H	SER50
H	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
H	ASN59

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)