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3FRT

The structure of human CHMP3 (residues 8 - 222).

Functional Information from GO Data
ChainGOidnamespacecontents
A0000421cellular_componentautophagosome membrane
A0000776cellular_componentkinetochore
A0000815cellular_componentESCRT III complex
A0001778biological_processplasma membrane repair
A0005515molecular_functionprotein binding
A0005546molecular_functionphosphatidylinositol-4,5-bisphosphate binding
A0005643cellular_componentnuclear pore
A0005737cellular_componentcytoplasm
A0005765cellular_componentlysosomal membrane
A0005768cellular_componentendosome
A0005769cellular_componentearly endosome
A0005770cellular_componentlate endosome
A0005771cellular_componentmultivesicular body
A0005828cellular_componentkinetochore microtubule
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006914biological_processautophagy
A0006915biological_processapoptotic process
A0006997biological_processnucleus organization
A0007034biological_processvacuolar transport
A0007080biological_processmitotic metaphase chromosome alignment
A0008333biological_processendosome to lysosome transport
A0010824biological_processregulation of centrosome duplication
A0015031biological_processprotein transport
A0016020cellular_componentmembrane
A0016236biological_processmacroautophagy
A0019076biological_processviral release from host cell
A0030496cellular_componentmidbody
A0031210molecular_functionphosphatidylcholine binding
A0031410cellular_componentcytoplasmic vesicle
A0031468biological_processnuclear membrane reassembly
A0031902cellular_componentlate endosome membrane
A0032467biological_processpositive regulation of cytokinesis
A0032509biological_processendosome transport via multivesicular body sorting pathway
A0032585cellular_componentmultivesicular body membrane
A0036258biological_processmultivesicular body assembly
A0039702biological_processviral budding via host ESCRT complex
A0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
A0044790biological_processsuppression of viral release by host
A0045324biological_processlate endosome to vacuole transport
A0046761biological_processviral budding from plasma membrane
A0051036biological_processregulation of endosome size
A0051258biological_processprotein polymerization
A0051301biological_processcell division
A0051469biological_processvesicle fusion with vacuole
A0061763biological_processmultivesicular body-lysosome fusion
A0061952biological_processmidbody abscission
A0070062cellular_componentextracellular exosome
A0071985biological_processmultivesicular body sorting pathway
A0090148biological_processmembrane fission
A0097352biological_processautophagosome maturation
A0140678molecular_functionmolecular function inhibitor activity
A1901673biological_processregulation of mitotic spindle assembly
A1902774biological_processlate endosome to lysosome transport
A1903541biological_processregulation of exosomal secretion
A1904930cellular_componentamphisome membrane
A1990381molecular_functionubiquitin-specific protease binding
A2000641biological_processregulation of early endosome to late endosome transport
B0000421cellular_componentautophagosome membrane
B0000776cellular_componentkinetochore
B0000815cellular_componentESCRT III complex
B0001778biological_processplasma membrane repair
B0005515molecular_functionprotein binding
B0005546molecular_functionphosphatidylinositol-4,5-bisphosphate binding
B0005643cellular_componentnuclear pore
B0005737cellular_componentcytoplasm
B0005765cellular_componentlysosomal membrane
B0005768cellular_componentendosome
B0005769cellular_componentearly endosome
B0005770cellular_componentlate endosome
B0005771cellular_componentmultivesicular body
B0005828cellular_componentkinetochore microtubule
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006914biological_processautophagy
B0006915biological_processapoptotic process
B0006997biological_processnucleus organization
B0007034biological_processvacuolar transport
B0007080biological_processmitotic metaphase chromosome alignment
B0008333biological_processendosome to lysosome transport
B0010824biological_processregulation of centrosome duplication
B0015031biological_processprotein transport
B0016020cellular_componentmembrane
B0016236biological_processmacroautophagy
B0019076biological_processviral release from host cell
B0030496cellular_componentmidbody
B0031210molecular_functionphosphatidylcholine binding
B0031410cellular_componentcytoplasmic vesicle
B0031468biological_processnuclear membrane reassembly
B0031902cellular_componentlate endosome membrane
B0032467biological_processpositive regulation of cytokinesis
B0032509biological_processendosome transport via multivesicular body sorting pathway
B0032585cellular_componentmultivesicular body membrane
B0036258biological_processmultivesicular body assembly
B0039702biological_processviral budding via host ESCRT complex
B0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
B0044790biological_processsuppression of viral release by host
B0045324biological_processlate endosome to vacuole transport
B0046761biological_processviral budding from plasma membrane
B0051036biological_processregulation of endosome size
B0051258biological_processprotein polymerization
B0051301biological_processcell division
B0051469biological_processvesicle fusion with vacuole
B0061763biological_processmultivesicular body-lysosome fusion
B0061952biological_processmidbody abscission
B0070062cellular_componentextracellular exosome
B0071985biological_processmultivesicular body sorting pathway
B0090148biological_processmembrane fission
B0097352biological_processautophagosome maturation
B0140678molecular_functionmolecular function inhibitor activity
B1901673biological_processregulation of mitotic spindle assembly
B1902774biological_processlate endosome to lysosome transport
B1903541biological_processregulation of exosomal secretion
B1904930cellular_componentamphisome membrane
B1990381molecular_functionubiquitin-specific protease binding
B2000641biological_processregulation of early endosome to late endosome transport
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsSITE: Important for autoinhibitory function
ChainResidueDetails
AVAL48
BVAL48

site_idSWS_FT_FI2
Number of Residues2
DetailsSITE: Interaction with STAMBP
ChainResidueDetails
AARG216
BARG216

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER200
BSER200

site_idSWS_FT_FI4
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
ChainResidueDetails
ALYS179
BLYS179

225946

PDB entries from 2024-10-09

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