Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3FC9

Crystal structure of the Mimivirus NDK +Kpn-N62L double mutant complexed with CDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0006183	biological_process	GTP biosynthetic process
A	0006228	biological_process	UTP biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
B	0004550	molecular_function	nucleoside diphosphate kinase activity
B	0006183	biological_process	GTP biosynthetic process
B	0006228	biological_process	UTP biosynthetic process
B	0006241	biological_process	CTP biosynthetic process
C	0004550	molecular_function	nucleoside diphosphate kinase activity
C	0006183	biological_process	GTP biosynthetic process
C	0006228	biological_process	UTP biosynthetic process
C	0006241	biological_process	CTP biosynthetic process
D	0004550	molecular_function	nucleoside diphosphate kinase activity
D	0006183	biological_process	GTP biosynthetic process
D	0006228	biological_process	UTP biosynthetic process
D	0006241	biological_process	CTP biosynthetic process
E	0004550	molecular_function	nucleoside diphosphate kinase activity
E	0006183	biological_process	GTP biosynthetic process
E	0006228	biological_process	UTP biosynthetic process
E	0006241	biological_process	CTP biosynthetic process
F	0004550	molecular_function	nucleoside diphosphate kinase activity
F	0006183	biological_process	GTP biosynthetic process
F	0006228	biological_process	UTP biosynthetic process
F	0006241	biological_process	CTP biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CTP A 142

Chain	Residue
A	LYS9
A	ASN113
A	ASP119
A	HIS53
A	TYR58
A	LEU62
A	ARG86
A	THR92
A	ARG103
A	ILE110
A	ARG111

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG B 142

Chain	Residue
B	CDP143
B	HOH156

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CDP B 143

Chain	Residue
B	LYS9
B	HIS53
B	TYR58
B	LEU62
B	ARG86
B	THR92
B	ARG103
B	ILE110
B	ARG111
B	ASN113
B	MG142
B	HOH156

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 142

Chain	Residue
C	ASP119
C	CDP143

site_id	AC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CDP C 143

Chain	Residue
C	LYS9
C	HIS53
C	TYR58
C	LEU62
C	ARG86
C	THR92
C	ARG103
C	ILE110
C	ARG111
C	ASN113
C	MG142
C	HOH148

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 142

Chain	Residue
D	CDP143

site_id	AC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CDP D 143

Chain	Residue
D	LYS9
D	HIS53
D	TYR58
D	LEU62
D	ARG86
D	THR92
D	ARG103
D	ILE110
D	ARG111
D	ASN113
D	MG142

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG E 142

Chain	Residue
E	CDP143

site_id	AC9
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CDP E 143

Chain	Residue
E	LYS9
E	TYR50
E	HIS53
E	TYR58
E	LEU62
E	ARG86
E	THR92
E	ARG103
E	ILE110
E	ARG111
E	ASN113
E	MG142

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG F 142

Chain	Residue
F	ARG86
F	CDP143

site_id	BC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CDP F 143

Chain	Residue
F	LYS9
F	HIS53
F	TYR58
F	LEU62
F	ARG86
F	THR92
F	ARG103
F	ILE110
F	ARG111
F	ASN113
F	MG142

Functional Information from PROSITE/UniProt

site_id	PS00469
Number of Residues	9
Details	NDPK Nucleoside diphosphate kinase (NDPK) active site signature. NliHASDSE

Chain	Residue	Details
A	ASN113-GLU121

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Pros-phosphohistidine intermediate => ECO:0000255\|PROSITE-ProRule:PRU10030

Chain	Residue	Details
A	HIS116
B	HIS116
C	HIS116
D	HIS116
E	HIS116
F	HIS116

site_id	SWS_FT_FI2
Number of Residues	30
Details	BINDING:

Chain	Residue	Details
A	LYS9
B	ASN113
C	LYS9
C	TYR58
C	ARG86
C	ARG103
C	ASN113
D	LYS9
D	TYR58
D	ARG86
D	ARG103
A	TYR58
D	ASN113
E	LYS9
E	TYR58
E	ARG86
E	ARG103
E	ASN113
F	LYS9
F	TYR58
F	ARG86
F	ARG103
A	ARG86
F	ASN113
A	ARG103
A	ASN113
B	LYS9
B	TYR58
B	ARG86
B	ARG103

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
A	ASN113
A	LYS9

site_id	CSA10
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
D	TYR50
D	LYS9

site_id	CSA11
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
E	TYR50
E	LYS9

site_id	CSA12
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
F	TYR50
F	LYS9

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
B	ASN113
B	LYS9

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
C	ASN113
C	LYS9

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
D	ASN113
D	LYS9

site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
E	ASN113
E	LYS9

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
F	ASN113
F	LYS9

site_id	CSA7
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
A	TYR50
A	LYS9

site_id	CSA8
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
B	TYR50
B	LYS9

site_id	CSA9
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsp

Chain	Residue	Details
C	TYR50
C	LYS9

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)