3F1O
Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains, with an internally-bound artificial ligand
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 2XY A 1 |
| Chain | Residue |
| A | SER246 |
| A | VAL302 |
| A | SER304 |
| A | TYR307 |
| A | MET309 |
| A | THR321 |
| A | CYS339 |
| A | ASN341 |
| A | HIS248 |
| A | MET252 |
| A | PHE254 |
| A | ALA277 |
| A | TYR281 |
| A | MET289 |
| A | SER292 |
| A | HIS293 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 351 |
| Chain | Residue |
| A | HOH161 |
| A | TYR278 |
| A | TYR281 |
| A | SER286 |
| B | GLU398 |
| B | CYS400 |
| B | PRO402 |
| B | GLN405 |
| B | ARG430 |
