3ER8

Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase complex with two fragments of RNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003746	molecular_function	translation elongation factor activity
A	0004483	molecular_function	mRNA (nucleoside-2'-O-)-methyltransferase activity
A	0006370	biological_process	7-methylguanosine mRNA capping
A	0031440	biological_process	regulation of mRNA 3'-end processing
B	0003746	molecular_function	translation elongation factor activity
B	0004483	molecular_function	mRNA (nucleoside-2'-O-)-methyltransferase activity
B	0006370	biological_process	7-methylguanosine mRNA capping
B	0031440	biological_process	regulation of mRNA 3'-end processing
C	0005524	molecular_function	ATP binding
C	0006397	biological_process	mRNA processing
C	0016740	molecular_function	transferase activity
C	0046872	molecular_function	metal ion binding
C	1990817	molecular_function	poly(A) RNA polymerase activity
D	0005524	molecular_function	ATP binding
D	0006397	biological_process	mRNA processing
D	0016740	molecular_function	transferase activity
D	0046872	molecular_function	metal ion binding
D	1990817	molecular_function	poly(A) RNA polymerase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: ACT_SITE => ECO:0000255|PIRSR:PIRSR015693-50

Chain	Residue	Details
C	ASP202
C	ASP204
D	ASP202
D	ASP204

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:16678106, ECO:0000269|PubMed:19446524, ECO:0007744|PDB:3ERC

Chain	Residue	Details
C	ASP202
B	GLU233
C	ASP204
C	ASP253
D	ASP202
D	ASP204
D	ASP253
B	ARG177
B	ASP182
B	SER205

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site_id	SWS_FT_FI3
Number of Residues	16
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00944, ECO:0000269|PubMed:8612277

Chain	Residue	Details
A	GLN39
B	TYR66
B	GLY68
B	GLY72
B	ASP95
B	ARG97
B	VAL116
B	ASP138
A	TYR66
A	GLY68
A	GLY72
A	ASP95
A	ARG97
A	VAL116
A	ASP138
B	GLN39

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