3EO3
Crystal structure of the N-acetylmannosamine kinase domain of human GNE protein
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 801 |
| Chain | Residue |
| A | HIS569 |
| A | CYS579 |
| A | CYS581 |
| A | CYS586 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 801 |
| Chain | Residue |
| B | HIS569 |
| B | CYS579 |
| B | CYS581 |
| B | CYS586 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 801 |
| Chain | Residue |
| C | CYS579 |
| C | CYS581 |
| C | CYS586 |
| C | HIS569 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE UNX A 1 |
| Chain | Residue |
| A | HIS604 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE UNX A 2 |
| Chain | Residue |
| A | ARG420 |
| A | ASP703 |
| A | ALA705 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE UNX B 3 |
| Chain | Residue |
| B | PRO704 |
| B | ALA705 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE UNX C 4 |
| Chain | Residue |
| C | GLU525 |
| C | GLY529 |
| C | GLN530 |
| C | ASP700 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"22343627","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2YHW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YHY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22343627","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2YHY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YI1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22343627","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2YI1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22343627","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2YHW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YHY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YI1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19841673","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22343627","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2YHW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YHY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YI1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EO3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q18 |
| Chain | Residue | Details |
| A | ASP517 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q18 |
| Chain | Residue | Details |
| B | ASP517 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q18 |
| Chain | Residue | Details |
| C | ASP517 |
