2YHW
High-resolution crystal structures of N-Acetylmannosamine kinase: Insights about substrate specificity, activity and inhibitor modelling.
Summary for 2YHW
| Entry DOI | 10.2210/pdb2yhw/pdb |
| Related | 2YHY 2YI1 |
| Descriptor | BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE/N-ACETYLMANNOSAMINE KINASE, 2-acetamido-2-deoxy-alpha-D-mannopyranose, ZINC ION, ... (10 entities in total) |
| Functional Keywords | transferase, sialic acid, mannac, rok family |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Cytoplasm (By similarity): Q9Y223 |
| Total number of polymer chains | 1 |
| Total formula weight | 38004.31 |
| Authors | Martinez, J.,Nguyen, L.D.,Tauberger, E.,Hinderlich, S.,Zimmer, R.,Tauberger, E.,Reutter, W.,Saenger, W.,Fan, H.,Moniot, S. (deposition date: 2011-05-08, release date: 2012-02-29, Last modification date: 2023-11-15) |
| Primary citation | Martinez, J.,Nguyen, L.D.,Tauberger, E.,Hinderlich, S.,Reutter, W.,Fan, H.,Saenger, W.,Moniot, S. Crystal Structures of N-Acetylmannosamine Kinase Provide Insights Into Enzyme Specificity and Inhibition J.Biol.Chem., 287:13656-, 2012 Cited by PubMed: 22343627DOI: 10.1074/JBC.M111.318170 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.64 Å) |
Structure validation
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