Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 501 |
| Chain | Residue |
| A | HIS77 |
| B | GLU169 |
| B | HOH590 |
| B | HOH597 |
| B | HOH614 |
| B | HOH624 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 502 |
| Chain | Residue |
| A | HOH574 |
| B | HIS77 |
| B | HOH557 |
| A | GLU169 |
| A | HOH547 |
| A | HOH557 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 503 |
| Chain | Residue |
| A | ASP212 |
| A | HOH565 |
| A | HOH578 |
| D | ASP212 |
| D | HOH754 |
| D | HOH764 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 502 |
| Chain | Residue |
| A | GLU138 |
| B | GLU138 |
| B | HOH613 |
| B | HOH632 |
| B | HOH760 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN B 503 |
| Chain | Residue |
| B | ASP212 |
| B | HOH539 |
| B | HOH567 |
| B | HOH576 |
| C | ASP212 |
| C | HOH543 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT B 1 |
| Chain | Residue |
| A | EDO19 |
| B | GLN79 |
| B | PRO80 |
| B | ASP81 |
| B | SER82 |
| B | HOH640 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT B 3 |
| Chain | Residue |
| A | THR45 |
| A | ASN63 |
| B | THR45 |
| B | ASN63 |
| B | HOH510 |
| B | HOH512 |
| B | HOH584 |
| B | HOH656 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN C 501 |
| Chain | Residue |
| C | HIS77 |
| D | EDO16 |
| D | GLU169 |
| D | HOH730 |
| D | HOH761 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 503 |
| Chain | Residue |
| C | ASP108 |
| C | GLU214 |
| C | HOH701 |
| C | HOH717 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 504 |
| Chain | Residue |
| B | ASP97 |
| B | HOH696 |
| C | GLU146 |
| C | HOH657 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN C 505 |
| Chain | Residue |
| C | EDO13 |
| C | GLU169 |
| C | HOH557 |
| C | HOH566 |
| D | HIS77 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT C 4 |
| Chain | Residue |
| C | GLN79 |
| C | PRO80 |
| C | ASP81 |
| C | SER82 |
| C | HOH564 |
| C | HOH597 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN D 502 |
| Chain | Residue |
| C | GLU138 |
| D | GLU138 |
| D | HOH823 |
| D | HOH887 |
| D | HOH946 |
| site_id | BC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ACT D 2 |
| Chain | Residue |
| C | THR45 |
| C | ASN63 |
| D | THR45 |
| D | ASN63 |
| D | ARG66 |
| D | HOH741 |
| D | HOH753 |
| D | HOH859 |
| D | HOH866 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT D 5 |
| Chain | Residue |
| D | GLN79 |
| D | PRO80 |
| D | ASP81 |
| D | SER82 |
| D | HOH842 |
| D | HOH909 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 6 |
| Chain | Residue |
| A | TYR172 |
| A | GLU206 |
| A | ILE209 |
| A | VAL211 |
| A | HOH516 |
| A | HOH610 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 12 |
| Chain | Residue |
| A | ALA96 |
| A | SER100 |
| A | TRP101 |
| A | HOH520 |
| A | HOH673 |
| A | HOH697 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 18 |
| Chain | Residue |
| A | GLN178 |
| A | LYS181 |
| A | ALA182 |
| A | GLN185 |
| A | HOH505 |
| A | HOH777 |
| D | ASP130 |
| site_id | CC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 19 |
| Chain | Residue |
| A | ALA149 |
| A | GLY151 |
| B | ACT1 |
| B | GLY78 |
| B | PRO80 |
| B | ASP81 |
| B | HOH599 |
| B | HOH712 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 25 |
| Chain | Residue |
| A | ALA62 |
| A | ILE121 |
| A | ASN122 |
| A | HOH510 |
| A | HOH523 |
| A | HOH718 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 14 |
| Chain | Residue |
| B | ASN122 |
| B | HOH518 |
| B | HOH521 |
| B | HOH677 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 15 |
| Chain | Residue |
| B | ALA96 |
| B | SER100 |
| B | TRP101 |
| B | HOH514 |
| B | HOH637 |
| B | HOH723 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 21 |
| Chain | Residue |
| B | EDO22 |
| B | MSE215 |
| C | ALA109 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 22 |
| Chain | Residue |
| B | EDO21 |
| B | ARG161 |
| C | LYS85 |
| C | HOH563 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 24 |
| Chain | Residue |
| A | GLN69 |
| B | TYR172 |
| B | HOH730 |
| B | HOH798 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 27 |
| Chain | Residue |
| A | SER124 |
| A | HOH708 |
| B | HOH750 |
| B | HOH781 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 29 |
| Chain | Residue |
| B | GLU206 |
| B | ILE209 |
| B | VAL211 |
| B | HOH534 |
| B | HOH722 |
| site_id | DC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 7 |
| Chain | Residue |
| C | ILE121 |
| C | ASN122 |
| C | HOH522 |
| C | HOH527 |
| C | HOH697 |
| site_id | DC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 11 |
| Chain | Residue |
| C | LYS49 |
| C | GLN60 |
| C | ALA96 |
| C | SER100 |
| C | TRP101 |
| C | HOH521 |
| C | HOH587 |
| site_id | DC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO C 13 |
| Chain | Residue |
| C | LEU55 |
| C | VAL57 |
| C | GLU169 |
| C | GLN171 |
| C | ZN505 |
| C | HOH557 |
| C | HOH566 |
| C | HOH721 |
| D | HIS77 |
| site_id | DC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 20 |
| Chain | Residue |
| B | ASP130 |
| C | LYS181 |
| C | ALA182 |
| C | GLN185 |
| C | HOH518 |
| site_id | DC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO D 8 |
| Chain | Residue |
| D | HOH717 |
| D | HOH947 |
| site_id | DC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 9 |
| Chain | Residue |
| D | LYS49 |
| D | ALA96 |
| D | SER100 |
| D | TRP101 |
| D | HOH724 |
| D | HOH853 |
| D | HOH855 |
| site_id | DC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 10 |
| Chain | Residue |
| A | ALA115 |
| A | HOH598 |
| B | GLN46 |
| B | GLU50 |
| B | HOH659 |
| D | ARG161 |
| site_id | DC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 16 |
| Chain | Residue |
| C | HIS77 |
| C | ZN501 |
| D | LEU55 |
| D | VAL57 |
| D | GLU169 |
| D | HOH730 |
| D | HOH761 |
| site_id | DC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 17 |
| Chain | Residue |
| A | ASP130 |
| D | GLN178 |
| D | ALA182 |
| D | GLN185 |
| D | HOH731 |
| site_id | EC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 23 |
| Chain | Residue |
| C | GLN69 |
| D | TYR172 |
| D | HOH958 |
| site_id | EC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 26 |
| Chain | Residue |
| D | ILE121 |
| D | ASN122 |
| D | HOH725 |
| D | HOH733 |
| D | HOH906 |
| site_id | EC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO D 28 |
| Chain | Residue |
| A | ARG161 |
| A | MSE215 |
