3DEG

Complex of elongating Escherichia coli 70S ribosome and EF4(LepA)-GMPPNP

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0003746	molecular_function	translation elongation factor activity
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006414	biological_process	translational elongation
C	0009268	biological_process	response to pH
C	0009409	biological_process	response to cold
C	0009651	biological_process	response to salt stress
C	0042274	biological_process	ribosomal small subunit biogenesis
C	0042802	molecular_function	identical protein binding
C	0043022	molecular_function	ribosome binding
C	0043023	molecular_function	ribosomal large subunit binding
C	0043024	molecular_function	ribosomal small subunit binding
C	0045727	biological_process	positive regulation of translation
C	0097216	molecular_function	guanosine tetraphosphate binding
D	0000049	molecular_function	tRNA binding
D	0000372	biological_process	Group I intron splicing
D	0002181	biological_process	cytoplasmic translation
D	0003735	molecular_function	structural constituent of ribosome
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0015935	cellular_component	small ribosomal subunit
D	0019843	molecular_function	rRNA binding
D	0022627	cellular_component	cytosolic small ribosomal subunit
D	0033120	biological_process	positive regulation of RNA splicing
D	0034336	molecular_function	misfolded RNA binding
D	0034337	biological_process	RNA folding
D	1990145	biological_process	maintenance of translational fidelity
H	0000027	biological_process	ribosomal large subunit assembly
H	0002181	biological_process	cytoplasmic translation
H	0003735	molecular_function	structural constituent of ribosome
H	0005515	molecular_function	protein binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0006415	biological_process	translational termination
H	0015968	biological_process	stringent response
H	0019843	molecular_function	rRNA binding
H	0022625	cellular_component	cytosolic large ribosomal subunit
H	0070180	molecular_function	large ribosomal subunit rRNA binding

Functional Information from PROSITE/UniProt

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR

Chain	Residue	Details
D	LYS42-ARG49

---

site_id	PS00301
Number of Residues	16
Details	G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DSmdlEReRGITIkaQ

Chain	Residue	Details
C	ASP42-GLN57

---

site_id	PS00359
Number of Residues	16
Details	RIBOSOMAL_L11 Ribosomal protein L11 signature. RsIeGTarSMGlVVeD

Chain	Residue	Details
H	ARG126-ASP141

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	182
Details	Domain: {"description":"tr-type G"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00071","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"3-methylthioaspartic acid","evidences":[{"source":"PubMed","id":"8844851","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"18723842","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"N,N,N-trimethylalanine","evidences":[{"source":"PubMed","id":"7004866","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Modified residue: {"description":"N6,N6,N6-trimethyllysine","evidences":[{"source":"PubMed","id":"7004866","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"21151122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
C	ASP14

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
C	HIS81

---