Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0007596 | biological_process | blood coagulation |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0006508 | biological_process | proteolysis |
| B | 0007596 | biological_process | blood coagulation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 402 |
| Chain | Residue |
| B | ARG263 |
| B | LYS266 |
| B | HOH414 |
| B | HOH429 |
| B | HOH628 |
| B | HOH629 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 44U B 1 |
| Chain | Residue |
| B | ASN131 |
| B | ILE209 |
| B | CYS231 |
| B | SER235 |
| B | SER256 |
| B | TRP257 |
| B | GLY258 |
| B | GLU259 |
| B | HOH532 |
| B | HOH547 |
| B | HOH572 |
| B | HIS79 |
| B | TYR83 |
| B | GLU130 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| B | LEU75-CYS80 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAceGDSGGPFV |
| Chain | Residue | Details |
| B | ASP229-VAL240 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| B | HIS79 | |
| B | ASP135 | |
| B | SER235 | |
| Chain | Residue | Details |
| B | ASN89 | |
