3D70

Crystal structure of E253A mutant of BMRR bound to 22-bp oligonucleotide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IMD A 302

Chain	Residue
A	ASN149

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IMD A 303

Chain	Residue
A	PRO144
A	ILE182
A	PHE224
A	PRO226

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE IMD A 304

Chain	Residue
A	ALA253
A	ILE255
A	TYR152
A	TYR170
A	TYR187
A	TYR229

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE IMD A 305

Chain	Residue
A	TYR5
A	TYR35
A	LEU231
A	GLN234
A	LYS235
A	LYS238

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE IMD A 306

Chain	Residue
A	SER58
A	TYR84
A	THR166
A	ASN167
A	ASN168
A	TYR260

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site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 308

Chain	Residue
A	SER175
A	PHE176
A	ARG188
A	ILE203
A	MET207
A	GLU208
A	ILE209
A	SER249
A	ASP250

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 309

Chain	Residue
A	ARG111
A	ILE132
A	ARG133
A	LEU195
A	ASN197

---

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GOL A 310

Chain	Residue
A	PRO144

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Functional Information from PROSITE/UniProt

site_id	PS00552
Number of Residues	23
Details	HTH_MERR_1 MerR-type HTH domain signature. GeVSklANVSikaLRyYDki.DLF

Chain	Residue	Details
A	GLY9-PHE31

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	19
Details	DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00254

Chain	Residue	Details
A	ILE8-LYS27

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