Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0046872 | molecular_function | metal ion binding |
A | 0070640 | biological_process | vitamin D3 metabolic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 23 |
Details | BINDING SITE FOR RESIDUE HEM A 413 |
Chain | Residue |
A | PHE95 |
A | ALA294 |
A | ARG297 |
A | ALA347 |
A | PHE348 |
A | GLY349 |
A | VAL352 |
A | HIS353 |
A | CYS355 |
A | GLY357 |
A | ALA361 |
A | ILE96 |
A | HOH506 |
A | HOH525 |
A | HOH529 |
A | HOH579 |
A | HIS103 |
A | ARG107 |
A | LEU241 |
A | ALA244 |
A | GLY245 |
A | THR248 |
A | THR249 |
site_id | AC2 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE VDX A 501 |
Chain | Residue |
A | THR81 |
A | PHE85 |
A | VAL88 |
A | ARG193 |
A | ILE293 |
A | GLY296 |
A | THR395 |
A | ILE396 |
A | HOH560 |
A | HOH593 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGfGVHQCLG |
Chain | Residue | Details |
A | PHE348-GLY357 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | THR81 | |
Chain | Residue | Details |
A | HIS103 | |
A | ARG107 | |
A | SER236 | |
A | ARG297 | |
A | HIS353 | |
Chain | Residue | Details |
A | ARG193 | |
A | ILE293 | |
Chain | Residue | Details |
A | CYS355 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1akd |
Chain | Residue | Details |
A | THR248 | |
A | GLU247 | |