Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070640 | biological_process | vitamin D3 metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM A 413 |
| Chain | Residue |
| A | PHE95 |
| A | ALA294 |
| A | ARG297 |
| A | ALA347 |
| A | PHE348 |
| A | GLY349 |
| A | VAL352 |
| A | HIS353 |
| A | CYS355 |
| A | GLY357 |
| A | ALA361 |
| A | ILE96 |
| A | HOH506 |
| A | HOH525 |
| A | HOH529 |
| A | HOH579 |
| A | HIS103 |
| A | ARG107 |
| A | LEU241 |
| A | ALA244 |
| A | GLY245 |
| A | THR248 |
| A | THR249 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE VDX A 501 |
| Chain | Residue |
| A | THR81 |
| A | PHE85 |
| A | VAL88 |
| A | ARG193 |
| A | ILE293 |
| A | GLY296 |
| A | THR395 |
| A | ILE396 |
| A | HOH560 |
| A | HOH593 |
Functional Information from PROSITE/UniProt
| site_id | PS00086 |
| Number of Residues | 10 |
| Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGfGVHQCLG |
| Chain | Residue | Details |
| A | PHE348-GLY357 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18937506","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18314962","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18314962","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18937506","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"18314962","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1akd |
| Chain | Residue | Details |
| A | THR248 | |
| A | GLU247 | |
