Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0004115 | molecular_function | 3',5'-cyclic-AMP phosphodiesterase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030553 | molecular_function | cGMP binding |
| A | 0046069 | biological_process | cGMP catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047555 | molecular_function | 3',5'-cyclic-GMP phosphodiesterase activity |
| A | 0141162 | biological_process | negative regulation of cAMP/PKA signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 876 |
| Chain | Residue |
| A | HIS617 |
| A | HIS653 |
| A | ASP654 |
| A | ASP764 |
| A | HOH903 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 877 |
| Chain | Residue |
| A | ASP654 |
| A | HIS657 |
| A | HOH903 |
| A | HOH905 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE WAN A 901 |
| Chain | Residue |
| A | HIS613 |
| A | GLU669 |
| A | HIS670 |
| A | PRO671 |
| A | LEU672 |
| A | TYR676 |
| A | ALA783 |
| A | PHE786 |
| A | MET816 |
| A | GLN817 |
| A | PHE820 |
| A | HOH914 |
| A | HOH934 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHrGvnNsY |
| Chain | Residue | Details |
| A | HIS653-TYR664 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS613 | |
| Chain | Residue | Details |
| A | HIS617 | |
| A | HIS653 | |
| A | ASP654 | |
| A | ASP764 | |
| Chain | Residue | Details |
| A | GLN817 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000255 |
| Chain | Residue | Details |
| A | SER102 | |
