3AVS

Catalytic fragment of UTX/KDM6A bound with N-oxyalylglycine, and Ni(II)

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE OGA A 1501

Chain	Residue
A	HOH7
A	ALA1238
A	NI1503
A	LYS1137
A	THR1143
A	HIS1146
A	GLU1148
A	SER1154
A	ASN1156
A	TRP1166
A	HIS1226

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1502

Chain	Residue
A	CYS1331
A	CYS1334
A	CYS1358
A	CYS1361

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NI A 1503

Chain	Residue
A	HOH276
A	HIS1146
A	GLU1148
A	HIS1226
A	OGA1501

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NI A 1504

Chain	Residue
A	HOH215
A	HIS1320

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NI A 1505

Chain	Residue
A	HIS1101

---

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1506

Chain	Residue
A	ARG1027

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 1507

Chain	Residue
A	HOH233
A	HIS1121

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1508

Chain	Residue
A	VAL1253
A	GLU1257
A	CYS1295
A	ARG1298

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 1509

Chain	Residue
A	TYR928
A	EDO1510

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 1510

Chain	Residue
A	HOH317
A	THR1030
A	LYS1034
A	TYR1035
A	LYS1083
A	EDO1509

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1511

Chain	Residue
A	HOH35
A	HOH211
A	ARG1213
A	PRO1214

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 1512

Chain	Residue
A	HOH176
A	HOH306
A	GLU946

---

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 1513

Chain	Residue
A	HOH190
A	LEU981
A	GLY982
A	SER985
A	ILE1159
A	EDO1514

---

site_id	BC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EDO A 1514

Chain	Residue
A	HOH107
A	HOH278
A	SER985
A	THR986
A	GLN1039
A	GLY1160
A	PRO1161
A	CYS1234
A	ASN1235
A	EDO1513

---

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 1515

Chain	Residue
A	HOH12
A	HOH84
A	HOH165
A	HOH219
A	ILE889
A	PRO891
A	ARG971

---

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 1516

Chain	Residue
A	HOH309
A	ALA1108
A	ARG1111
A	SER1114
A	ALA1115

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	163
Details	Domain: {"description":"JmjC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00538","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	26
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	13
Details	Compositional bias: {"description":"Pro residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22002947","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---