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2ZME

Integrated structural and functional model of the human ESCRT-II complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000814cellular_componentESCRT II complex
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005667cellular_componenttranscription regulator complex
A0005737cellular_componentcytoplasm
A0005768cellular_componentendosome
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006357biological_processregulation of transcription by RNA polymerase II
A0008289molecular_functionlipid binding
A0010008cellular_componentendosome membrane
A0010628biological_processpositive regulation of gene expression
A0015031biological_processprotein transport
A0016020cellular_componentmembrane
A0016236biological_processmacroautophagy
A0016247molecular_functionchannel regulator activity
A0031902cellular_componentlate endosome membrane
A0032456biological_processendocytic recycling
A0036258biological_processmultivesicular body assembly
A0042176biological_processregulation of protein catabolic process
A0042803molecular_functionprotein homodimerization activity
A0043328biological_processprotein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
A0043405biological_processregulation of MAP kinase activity
A0045022biological_processearly endosome to late endosome transport
A0045732biological_processpositive regulation of protein catabolic process
A0048471cellular_componentperinuclear region of cytoplasm
A0055037cellular_componentrecycling endosome
A0061635biological_processregulation of protein complex stability
A0070062cellular_componentextracellular exosome
A0071985biological_processmultivesicular body sorting pathway
A0090148biological_processmembrane fission
A1903543biological_processpositive regulation of exosomal secretion
B0000814cellular_componentESCRT II complex
B0032509biological_processendosome transport via multivesicular body sorting pathway
B0043130molecular_functionubiquitin binding
C0000814cellular_componentESCRT II complex
C0071985biological_processmultivesicular body sorting pathway
D0000814cellular_componentESCRT II complex
D0071985biological_processmultivesicular body sorting pathway
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Omega-N-methylarginine => ECO:0007744|PubMed:24129315
ChainResidueDetails
AARG4

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PDB entries from 2024-07-24

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