2Z7X
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002224 | biological_process | toll-like receptor signaling pathway |
| A | 0004888 | molecular_function | transmembrane signaling receptor activity |
| A | 0006955 | biological_process | immune response |
| A | 0016020 | cellular_component | membrane |
| B | 0002224 | biological_process | toll-like receptor signaling pathway |
| B | 0004888 | molecular_function | transmembrane signaling receptor activity |
| B | 0006955 | biological_process | immune response |
| B | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"LRR 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"LRR 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"LRR 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 48 |
| Details | Repeat: {"description":"LRR 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 48 |
| Details | Repeat: {"description":"LRR 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"LRR 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"LRR 7"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 52 |
| Details | Repeat: {"description":"LRR 8"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 54 |
| Details | Repeat: {"description":"LRR 9"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 58 |
| Details | Repeat: {"description":"LRR 10"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 56 |
| Details | Repeat: {"description":"LRR 11"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"LRR 12"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 52 |
| Details | Repeat: {"description":"LRR 13"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 50 |
| Details | Repeat: {"description":"LRR 14"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 44 |
| Details | Repeat: {"description":"LRR 15"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 38 |
| Details | Repeat: {"description":"LRR 16"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"LRR 17"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 21 |
| Details | Repeat: {"description":"LRR 18"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI19 |
| Number of Residues | 23 |
| Details | Repeat: {"description":"LRR 19"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI20 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with bacterial lipopeptide"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI21 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15173186","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17889651","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI22 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"17889651","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI23 |
| Number of Residues | 3 |
| Details | Region: {"description":"Interaction with bacterial lipopeptide"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI24 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI25 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"17889651","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
