Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000413 | biological_process | protein peptidyl-prolyl isomerization |
A | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
A | 0006457 | biological_process | protein folding |
B | 0000413 | biological_process | protein peptidyl-prolyl isomerization |
B | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
B | 0006457 | biological_process | protein folding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE CIT A 3001 |
Chain | Residue |
A | GLY50 |
A | HOH2257 |
A | HOH2258 |
A | SER51 |
A | THR52 |
A | HIS70 |
A | GLY80 |
A | SER81 |
A | ARG82 |
A | LYS155 |
A | HOH2149 |
site_id | AC2 |
Number of Residues | 30 |
Details | BINDING SITE FOR CHAIN M OF CYCLOSPORIN A |
Chain | Residue |
A | ARG55 |
A | PHE60 |
A | GLN63 |
A | GLY72 |
A | ALA101 |
A | ASN102 |
A | ALA103 |
A | GLN111 |
A | PHE113 |
A | TRP121 |
A | HIS126 |
A | HOH2135 |
B | LEU5 |
B | SER81 |
B | ALA103 |
B | GLU134 |
B | LEU164 |
B | HOH2161 |
B | HOH2199 |
B | HOH2244 |
M | HOH2001 |
M | HOH2002 |
M | HOH2003 |
M | HOH2004 |
M | HOH2005 |
M | HOH2006 |
M | HOH2007 |
M | HOH2008 |
M | HOH2009 |
M | HOH2010 |
site_id | AC3 |
Number of Residues | 25 |
Details | BINDING SITE FOR CHAIN N OF CYCLOSPORIN A |
Chain | Residue |
A | GLY104 |
A | HOH2197 |
B | ARG37 |
B | GLU43 |
B | ARG55 |
B | PHE60 |
B | GLN63 |
B | GLY72 |
B | ALA101 |
B | ASN102 |
B | GLN111 |
B | PHE113 |
B | TRP121 |
B | HIS126 |
B | GLN163 |
B | LEU164 |
B | SER165 |
B | HOH2110 |
B | HOH2124 |
B | HOH2218 |
N | HOH2001 |
N | HOH2005 |
N | HOH2006 |
N | HOH2007 |
N | HOH2008 |
Functional Information from PROSITE/UniProt
site_id | PS00170 |
Number of Residues | 18 |
Details | CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YkgStFHRVIpsFMcQAG |
Chain | Residue | Details |
A | TYR48-GLY65 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | LYS25 | |
B | LYS25 | |
Chain | Residue | Details |
A | LYS44 | |
A | ILE133 | |
A | LYS148 | |
B | LYS44 | |
B | ILE133 | |
B | LYS148 | |
Chain | Residue | Details |
A | LYS125 | |
B | LYS125 | |
Chain | Residue | Details |
A | CYS161 | |
B | CYS161 | |