Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000413 | biological_process | protein peptidyl-prolyl isomerization |
| A | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| A | 0006457 | biological_process | protein folding |
| B | 0000413 | biological_process | protein peptidyl-prolyl isomerization |
| B | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| B | 0006457 | biological_process | protein folding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CIT A 3001 |
| Chain | Residue |
| A | GLY50 |
| A | HOH2257 |
| A | HOH2258 |
| A | SER51 |
| A | THR52 |
| A | HIS70 |
| A | GLY80 |
| A | SER81 |
| A | ARG82 |
| A | LYS155 |
| A | HOH2149 |
| site_id | AC2 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR CHAIN M OF CYCLOSPORIN A |
| Chain | Residue |
| A | ARG55 |
| A | PHE60 |
| A | GLN63 |
| A | GLY72 |
| A | ALA101 |
| A | ASN102 |
| A | ALA103 |
| A | GLN111 |
| A | PHE113 |
| A | TRP121 |
| A | HIS126 |
| A | HOH2135 |
| B | LEU5 |
| B | SER81 |
| B | ALA103 |
| B | GLU134 |
| B | LEU164 |
| B | HOH2161 |
| B | HOH2199 |
| B | HOH2244 |
| M | HOH2001 |
| M | HOH2002 |
| M | HOH2003 |
| M | HOH2004 |
| M | HOH2005 |
| M | HOH2006 |
| M | HOH2007 |
| M | HOH2008 |
| M | HOH2009 |
| M | HOH2010 |
| site_id | AC3 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR CHAIN N OF CYCLOSPORIN A |
| Chain | Residue |
| A | GLY104 |
| A | HOH2197 |
| B | ARG37 |
| B | GLU43 |
| B | ARG55 |
| B | PHE60 |
| B | GLN63 |
| B | GLY72 |
| B | ALA101 |
| B | ASN102 |
| B | GLN111 |
| B | PHE113 |
| B | TRP121 |
| B | HIS126 |
| B | GLN163 |
| B | LEU164 |
| B | SER165 |
| B | HOH2110 |
| B | HOH2124 |
| B | HOH2218 |
| N | HOH2001 |
| N | HOH2005 |
| N | HOH2006 |
| N | HOH2007 |
| N | HOH2008 |
Functional Information from PROSITE/UniProt
| site_id | PS00170 |
| Number of Residues | 18 |
| Details | CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YkgStFHRVIpsFMcQAG |
| Chain | Residue | Details |
| A | TYR48-GLY65 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 312 |
| Details | Domain: {"description":"PPIase cyclophilin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00156","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q99KR7","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q99KR7","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q99KR7","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"S-nitrosocysteine","evidences":[{"source":"UniProtKB","id":"Q99KR7","evidenceCode":"ECO:0000250"}]} |
