2YKG

Structural insights into RNA recognition by RIG-I

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0005524	molecular_function	ATP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 927

Chain	Residue
A	CYS810
A	CYS813
A	CYS864
A	CYS869

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 1923

Chain	Residue
A	LYS270
A	THR271
A	HOH2028
A	PRO265
A	THR266
A	GLY267
A	CYS268
A	GLY269

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
A	ALA264

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01125

Chain	Residue	Details
A	CYS810
A	CYS813
A	CYS864
A	CYS869

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: (Microbial infection) Deamidated asparagine; by herpes simplex virus 1/HHV-1 UL37 => ECO:0000269|PubMed:27866900

Chain	Residue	Details
A	ASN495
A	ASN549

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by CK2 => ECO:0000269|PubMed:21068236

Chain	Residue	Details
A	THR770

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site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: Phosphoserine; by CK2 => ECO:0000269|PubMed:21068236

Chain	Residue	Details
A	SER854
A	SER855

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site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS858

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site_id	SWS_FT_FI7
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:Q6Q899

Chain	Residue	Details
A	LYS812

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