Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| A | 0039694 | biological_process | viral RNA genome replication |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| B | 0039694 | biological_process | viral RNA genome replication |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE GTP A 1001 |
| Chain | Residue |
| A | LYS141 |
| A | THR390 |
| A | ARG394 |
| A | GLU446 |
| A | SER556 |
| A | GLY557 |
| A | GTP1002 |
| A | MG1004 |
| A | HOH2230 |
| A | HOH2281 |
| A | HOH2391 |
| A | GLU143 |
| A | HOH2393 |
| A | HOH2394 |
| A | HOH2395 |
| A | PHE145 |
| A | ARG158 |
| A | ILE160 |
| A | SER282 |
| A | THR287 |
| A | SER367 |
| A | ARG386 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GTP A 1002 |
| Chain | Residue |
| A | ARG48 |
| A | LYS51 |
| A | LYS141 |
| A | ARG158 |
| A | ASP220 |
| A | ASP225 |
| A | SER282 |
| A | ASP318 |
| A | GTP1001 |
| A | MG1005 |
| A | HOH2145 |
| A | HOH2395 |
| A | HOH2396 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GTP A 1003 |
| Chain | Residue |
| A | LYS69 |
| A | GLU70 |
| A | ALA73 |
| A | ALA74 |
| A | LYS77 |
| B | CYS110 |
| B | ALA112 |
| site_id | AC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE GTP B 1001 |
| Chain | Residue |
| B | LYS141 |
| B | GLU143 |
| B | ARG158 |
| B | SER282 |
| B | THR287 |
| B | SER367 |
| B | ARG386 |
| B | THR390 |
| B | ARG394 |
| B | GLU446 |
| B | SER556 |
| B | GLY557 |
| B | GTP1002 |
| B | MG1005 |
| B | HOH2233 |
| B | HOH2390 |
| B | HOH2391 |
| B | HOH2392 |
| B | HOH2393 |
| B | HOH2394 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GTP B 1002 |
| Chain | Residue |
| B | ARG48 |
| B | LYS141 |
| B | ARG158 |
| B | ASP220 |
| B | ASP225 |
| B | SER282 |
| B | ASP318 |
| B | GTP1001 |
| B | MG1006 |
| B | HOH2395 |
| B | HOH2396 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 1004 |
| Chain | Residue |
| A | GTP1001 |
| A | HOH2281 |
| A | HOH2394 |
| A | HOH2396 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 1005 |
| Chain | Residue |
| A | ASP220 |
| A | THR221 |
| A | GTP1002 |
| A | HOH2187 |
| A | HOH2242 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 1006 |
| Chain | Residue |
| A | TYR358 |
| A | ASP359 |
| B | ASP437 |
| B | ARG514 |
| B | HOH2369 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 1005 |
| Chain | Residue |
| B | ARG158 |
| B | GTP1001 |
| B | HOH2393 |
| B | HOH2394 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 1006 |
| Chain | Residue |
| B | ASP220 |
| B | THR221 |
| B | GTP1002 |
| B | HOH2247 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 236 |
| Details | Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P26663","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine; by host","evidences":[{"source":"UniProtKB","id":"P26662","evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | |
| Details | M-CSA 776 |
| site_id | MCSA2 |
| Number of Residues | |
| Details | M-CSA 776 |
