2X1X

CRYSTAL STRUCTURE OF VEGF-C IN COMPLEX WITH DOMAINS 2 AND 3 OF VEGFR2 IN A TETRAGONAL CRYSTAL FORM

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0008083	molecular_function	growth factor activity
E	0016020	cellular_component	membrane
R	0005021	molecular_function	vascular endothelial growth factor receptor activity
R	0005524	molecular_function	ATP binding
R	0006468	biological_process	protein phosphorylation
R	0016020	cellular_component	membrane
R	0019838	molecular_function	growth factor binding
R	0048010	biological_process	vascular endothelial growth factor receptor signaling pathway

Functional Information from PROSITE/UniProt

site_id	PS00249
Number of Residues	13
Details	PDGF_1 Platelet-derived growth factor (PDGF) family signature. PPCVsvyRCGGCC

Chain	Residue	Details
E	PRO154-CYS166

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:20145116

Chain	Residue	Details
R	ASN143
E	ASN205

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site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
R	ASN158

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site_id	SWS_FT_FI3
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:20145116, ECO:0000269|PubMed:21827946

Chain	Residue	Details
R	ASN245
R	ASN318

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