Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0008398 | molecular_function | sterol 14-demethylase activity |
A | 0016020 | cellular_component | membrane |
A | 0016126 | biological_process | sterol biosynthetic process |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0046872 | molecular_function | metal ion binding |
B | 0004497 | molecular_function | monooxygenase activity |
B | 0005506 | molecular_function | iron ion binding |
B | 0008398 | molecular_function | sterol 14-demethylase activity |
B | 0016020 | cellular_component | membrane |
B | 0016126 | biological_process | sterol biosynthetic process |
B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
B | 0020037 | molecular_function | heme binding |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE HEM A 1450 |
Chain | Residue |
A | TYR103 |
A | THR299 |
A | LEU356 |
A | VAL359 |
A | ARG361 |
A | GLY414 |
A | PHE415 |
A | GLY416 |
A | HIS420 |
A | CYS422 |
A | ILE423 |
A | TYR116 |
A | ALA428 |
A | TPF1460 |
A | HOH2212 |
A | HOH2214 |
A | HOH2215 |
A | LEU127 |
A | LEU134 |
A | ALA288 |
A | ALA291 |
A | GLY292 |
A | THR295 |
A | SER296 |
site_id | AC2 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE TPF A 1460 |
Chain | Residue |
A | TYR103 |
A | MET106 |
A | TYR116 |
A | ALA287 |
A | PHE290 |
A | ALA291 |
A | LEU356 |
A | HEM1450 |
A | HOH2214 |
A | HOH2216 |
A | HOH2217 |
site_id | AC3 |
Number of Residues | 22 |
Details | BINDING SITE FOR RESIDUE HEM B 1450 |
Chain | Residue |
B | TYR103 |
B | TYR116 |
B | LEU127 |
B | ALA288 |
B | ALA291 |
B | GLY292 |
B | THR295 |
B | SER296 |
B | THR299 |
B | LEU356 |
B | VAL359 |
B | ARG361 |
B | GLY414 |
B | PHE415 |
B | GLY416 |
B | HIS420 |
B | CYS422 |
B | ILE423 |
B | GLY424 |
B | TPF1460 |
B | HOH2035 |
B | HOH2211 |
site_id | AC4 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE TPF B 1460 |
Chain | Residue |
B | TYR103 |
B | PHE110 |
B | TYR116 |
B | ALA287 |
B | ALA291 |
B | LEU356 |
B | HEM1450 |
B | HOH2035 |
B | HOH2212 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGaGVHKCIG |
Chain | Residue | Details |
A | PHE415-GLY424 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | CYS422 | |
B | CYS422 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1akd |
Chain | Residue | Details |
A | HIS294 | |
A | THR295 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1akd |
Chain | Residue | Details |
B | HIS294 | |
B | THR295 | |