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2W8Y

RU486 bound to the progesterone receptor in a destabilized agonistic conformation

Functional Information from PDB Data
site_idAC1
Number of Residues18
DetailsBINDING SITE FOR RESIDUE 486 A 1000
ChainResidue
ALEU715
AMET759
AARG766
APHE794
ALEU797
AMET801
ATYR890
ACYS891
AMET909
AHOH2016
ALEU718
AASN719
ALEU721
AGLY722
AGLU723
AGLN725
ATRP755
AMET756

site_idAC2
Number of Residues10
DetailsBINDING SITE FOR RESIDUE NDR B 1000
ChainResidue
BLEU715
BLEU718
BASN719
BGLN725
BMET756
BMET759
BARG766
BMET801
BTYR890
BCYS891

site_idAC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE EDO B 1934
ChainResidue
BTRP765
BHIS770
BGLN815

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A 1934
ChainResidue
APRO737
AGLY738
AARG740
AASN741
AHOH2106

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:9620806
ChainResidueDetails
AARG766
BARG766

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PDB entries from 2024-11-06

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