2UZR

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer (AKT1-PH_E17K)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0043491	biological_process	protein kinase B signaling

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:12176338, ECO:0000269|PubMed:12964941

Chain	Residue	Details
A	LYS14
A	ARG23
A	ASN53
A	ARG86

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:21775285

Chain	Residue	Details
A	LYS14
A	LYS20

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