Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0004672 | molecular_function | protein kinase activity |
B | 0004713 | molecular_function | protein tyrosine kinase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE GW7 A 1 |
Chain | Residue |
A | ALA749 |
A | GLY802 |
A | CYS803 |
A | LEU850 |
A | THR860 |
A | ASP861 |
A | PHE862 |
A | HOH1011 |
A | LYS751 |
A | ARG782 |
A | LEU783 |
A | LEU794 |
A | THR796 |
A | GLN797 |
A | LEU798 |
A | MET799 |
site_id | AC2 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE GW7 B 1 |
Chain | Residue |
B | ALA749 |
B | LYS751 |
B | MET772 |
B | ARG782 |
B | LEU783 |
B | LEU794 |
B | THR796 |
B | GLN797 |
B | MET799 |
B | CYS803 |
B | GLU806 |
B | LEU850 |
B | THR860 |
B | ASP861 |
B | PHE862 |
B | HOH1019 |
B | HOH1067 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 28 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGSGAFGTVYkGiwvpegetvkip......VAIK |
Chain | Residue | Details |
A | LEU724-LYS751 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. LVHrDLAARNVLV |
Chain | Residue | Details |
A | LEU839-VAL851 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP843 | |
B | ASP843 | |
Chain | Residue | Details |
A | LEU724 | |
A | LYS751 | |
A | GLN797 | |
A | ASP843 | |
B | LEU724 | |
B | LYS751 | |
B | GLN797 | |
B | ASP843 | |
Chain | Residue | Details |
A | TYR875 | |
B | TYR875 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ARG847 | |
A | ASP843 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
B | ARG847 | |
B | ASP843 | |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ALA845 | |
A | ASP843 | |
site_id | CSA4 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
B | ALA845 | |
B | ASP843 | |
site_id | CSA5 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ASN848 | |
A | ALA845 | |
A | ASP843 | |
site_id | CSA6 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
B | ASN848 | |
B | ALA845 | |
B | ASP843 | |